Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
how can loop diuretics lead to hyperglycemia?
|
loop diuretics can lead to hypokalemia, and as K stimulates insulin, this will lead to low insulin and hyperglycemia
|
|
what are some side effects of loops, in addition to the serum chemistries?
|
allergy and ototoxicity
|
|
if someone is allergic to sulfas, and you need a Loop diuretic, what can you Rx?
|
ethacrynic acid
|
|
how can thiazide diuretics affect:
K H+ Uric Acid Sugar Levels Calcium [Na] Cholesterol |
K and H+ : thiazides can lead to hypokalemic acidosis as more will be excreted in the CD as excess Na will be reabsorbed there
Uric Acid - more will be reabsorbed due to hypovolemia -can lead to hyperglycemia -can lead to hypercalcemia, as Ca competes with Na in DCT -can lead to hyponatremia -can lead to high LDL and low HDL |
|
what drug might promote Ca2+ reabsorption for kidney stones?
|
thiazide diuretics, as Ca competes with Na in the DCT
|
|
what is the first line drug for HTN regarding diuretics?
|
thiazides
|
|
what diuretic is first indicated in treating pulmonary/peripheral edema and ascites?
|
Loops (for ascites it is used secondarily with spironolactone)
|
|
Spironolactone - effects on plasma:
main uses: |
plasma: leads to hypokalemia, acidosis
main use: to correct K and H+ imbalance from Loop and Thiazide diuretics, or if excess [Aldo]. also for severe HF to slow remodeling |
|
osmotic diuretics like Mannitol can alleviate ____ edema yet they can also lead to ____ edema. other uses?
|
can help w/ cerebral edema but can lead to pulmonary edema
- can also be used for acute closed-angle glaucoma; maintain perfusion of kidney in times of acute kidney failure |
|
options to treat SIADH?
|
Lithium, or Demeclocycline - both are "ADH antagonists" thus lead to diabetes insipidus
|
|
most important diuretic for ascites:
|
spironolactone
|