Immunodeficiency Virus: A Case Study

Improved Essays
HIV stands for human immunodeficiency virus. HIV is able to hide for a long period of time in the cells and attack the immune system, specially the T cells. These cells are in the body to fight infections and diseases, but when someone gets infected with HIV these invades the T cells and makes copies of itself and destroys them. As time goes by HIV can destroy many T cells, which affects the body by making the body weak and not able to fight infections and diseases anymore. HIV id divided into three stages, the early stage, the clinical latency stage, and the final stage.
The virus can be transmitted through different ways. It can be transmitted through body fluids such as blood, semen, rectal fluids, vaginal fluids, and breast milk. In order
…show more content…
At the end of 2013 35.5 million living with HIV and approximately 2.1 million got infected globally. HIV is most prevalent in Sub Saharan Africa with 24.5 million people living with HIV in 2013 according to the World Health Organization. This region of the world accounts for almost up to 70 percent of HIV infections globally. In 2012 there was about 1.6 million new HIV infections and nearly 1.2 million AIDS related …show more content…
The fist treatment for HIV was called AZT in 1987. Later on approximately more than 30 drugs were approved to treat people with HIV/AIDS and many more are under development. Currently there are five different HIV drugs that are classified to attack the virus at different points of the cycle. Taking three different medications controls the virus better and protects the immune system. This process is called Antiretroviral Therapy (ART). Some examples of antiretroviral medications include Nucleoside/non-nucleoside reverse transcriptase inhibitors also called “nuke” that help block the most important step of HIV reproduction process. These two medicines block the enzyme reverse transcriptase and prevent the virus from making copies of its DNA. Another include protease inhibitors that blocks the strands of DNA from getting cut into functional pieces. A third medication is called Fusion inhibitors that blocks the virus from entering the cells. Through receptor sites HIV attach and bond to the CD4 cells which prevent the virus from entering into healthy cells. Lastly integrase inhibitor disable the integrase protein that HIV uses to insert the genetic material into the CD4 cells. However the treatment have some side effects including diarrhea, nausea, heart disease, weakened bones, shortness of breath, and skin rash. Even though it has side effect these treatment has help people with HIV live longer and

Related Documents

  • Improved Essays

    Ccr5 Unit 1 Term Paper

    • 437 Words
    • 2 Pages

    A new study has been developed in hopes of treating and curing HIV. The main agent is a protein called ZFN that can delete another protein called CCR5. The CCR5 is required for certain types of HIV to enter and infect your T-Cells. T-Cells are white blood cells the body uses to fight HIV, but the most important of these are CD4 T-Cells. HIV is known to infect the CD4+ T-Cells in your blood.…

    • 437 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    HIV is a virus transmitted through contact with infected bodily fluids. The virus weakens the body’s defenses against other infections (Merck Manual, 2015). A large number of infected people remain feeling “well” for many years, but if they do not seek treatment their condition will worse and eventually have their immune system be ineffective (Merck Manual, 2015). Although no actual cure exists, some treatments are available. According to the Manual, “HIV drugs…can stop HIV from reproducing, strengthen the immune system, and thus make people less susceptible to infection, but the drugs cannot, with rare exceptions, eliminate HIV” (Merck Manual, 2015).…

    • 821 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    One of the most common known Sexual Transmitted Diseases (STD’s) that has become a global health issue is the Human Immunodeficiency Virus better known as HIV. HIV targets the immune system and weakens people’s surveillance and defense systems against infections and some types of cancer (WHO, 2014). HIV targets specific cells in the immune system they are the CD4 cells or preferably known as T cells (CDC, 2015). HIV has different symptoms depending on the stage the virus is in. The reason so many people have HIV is because in the beginning the contaminated person does not know they have the virus thus, leading to the spread of the virus.…

    • 902 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Some doctors use a drug called cyclosporine to slow down the growth and activity of immune cells called T cells. With the connection of the patients possibly having HIV, the doctor may also give the patient an antiviral drug. With the extra diagnosis of HIV or HHV-8 infection, these medicines can fight these viruses. Antivirals that are used include foscarnet, ganciclovir, and valganciclovir (Castleman…

    • 603 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Hiv Case Study

    • 636 Words
    • 3 Pages

    When the virus enters it adheres to a special dendritic cell referred to as DC-SIGN in which the dendritic cell is not effected which allows it to be transported to the lymph nodes. The HIV binds via gp120 to CD4 on th cells which changes gp120 allowing it to be a co-receptor thus allowing it to bind to CCR5 or CXCR4. After this binding, the gp41 conformation is changed which reduces the T cell membrane allowing the virus to fuse to the cell. The virus’ reverse transcriptase process begins after moving into the core of the cell to make a dna copy from the rna copy and that then moves into the nucleus of the cell and ultimately fuses to the membrane of the host's…

    • 636 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    HIV attacks the immune system so the body can not fight germs and diseases. A person infected with the virus in the body leads to the rest of his life. The human immunodeficiency virus is part of the genre Lentivirus.1 These constitute a group within the family Retroviridae.2 Viruses of this group have common morphological and biological properties. Several species are attacked by the lentivirus, whose main feature is a long incubation period that leads to disease after several years.3…

    • 407 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Burroughs Wellcome Failure

    • 1373 Words
    • 6 Pages

    For users who had a negative reaction to AZT used DDI, a competitor’s antiviral drug that is used to slow the reproduction and growth of the HIV virus. That same year of 1987, there was a count of 27,016 AIDS cases in condensed metropolitan cities in the United States. Retrovir’s initial go-to-market price was $188 per hundred 100-milligram capsules, a Medicaid Program partially financed this cost for consumers.…

    • 1373 Words
    • 6 Pages
    Improved Essays
  • Great Essays

    The fourth medicinal treatment slows the onset of HIV/AIDs by blocking the virus from entering the CD4 cells altogether. The entry or fusion inhibitor treatment has proven to be the most successful treatment thus far but alas still does not cure the disease. Examples of medications in this treatment includes enfuvirtide (Fuzeon) and maraviroc (Selzentry) (Mayo clinic 2015). Lastly the final treatment proven to slow HIV/Aids is called integrase inhibitors. This treatment prevent the virus by breaking down or disabling integrase, which is a protein needed by the virus to insert its genetic material into the CD4 cells’ nucleus.…

    • 1798 Words
    • 8 Pages
    Great Essays
  • Great Essays

    Viral loads and adverse events should be monitored throughout therapy to ensure virologic response, and antiretroviral therapy should be modified if virologic failure occurs Adverse effects are common with antiretroviral therapy and include spontaneous bleeding, skin conditions, renal and hepatic effects, hypersensitivity reactions, osteoporosis, and cardiac events The majority of patients with AIDS who receive treatment are still alive 3 years after AIDS diagnosis URGENT ACTION Hypersensitivity reactions to abacavir require urgent medical attention because they can result in death within several hours of onset 13 PITFALLS HIV RNA viral load testing can detect HIV 11-12 days after acute infection, but HIV antibodies usually take approximately 21 days to detect; therefore, viral load testing should be repeated with ELISA within 4-6 weeks of acute infection…

    • 1697 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    AIDS In Africa

    • 1167 Words
    • 5 Pages

    HIV (human immunodeficiency virus) is the virus responsible for causing AIDS (acquired immunodeficiency syndrome). The virus leaves the human immune system weak and renders infected individuals vulnerable to other illnesses. HIV has been thought to have originated on the African continent and is becoming an increasing medical issue there. The documentary AIDS in Africa details the rise and impact of the rate of HIV infection and AIDS throughout the African continent. In the documentary, various medical professionals are interviewed for their perspective, and all express concern over the rising rates of infection and lack of resources for prevention in Africa.…

    • 1167 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Charlie Sheen Case

    • 1235 Words
    • 5 Pages

    A virus contributes to HIV infections in humans and it affects the immune system and weakens it in such a way that the body cannot fight other diseases. If not well managed the virus leads to a progressive failure in of the immune system. It can be life threatening if no well managed since it allows opportunistic infections to thrive in the human body. The average survival time for a person infected with the HIV without treatment is between nine to eleven years. A person can be infected through various ways.…

    • 1235 Words
    • 5 Pages
    Improved Essays
  • Superior Essays

    'Acquired Immune Deficiency Virus (AIDS) is caused by a human immunodeficiency virus (HIV) that weakens the immune system , making the body susceptible to and unable to recover from op­portunistic diseases that lead to death' (USAID, 2010, pp.173). It is one of the major challenges for Pub­lic Health and it is the world's leading infectious killer. According to the WHO, 35 million people are living with HIV worldwide. In middle and low income countries is the majority of infec­ted people. In 2013, 2.1 million new infections occurred in low and middle income countries (WHO, 2013).…

    • 2493 Words
    • 10 Pages
    Superior Essays
  • Improved Essays

    Although, there is no cure for HIV the treatment method begins with antiretroviral therapy, which consists of a combination of HIV medications. This form of treatment hinders the HIV virus from multiplying and reduces the amount of HIV in the infected individual. However, just like with any medication there may be side effects associated with the medicines that may make the treatment process difficult for some infected individuals. Transmission is the second misconstrued topic of HIV that many individuals struggle to comprehend. HIV is transmitted in a variety of ways including via…

    • 776 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    Human Immune Deficiency means to lack the defense mechanisms necessary to fight against simple viruses like the common cold. The virus attacks the helper T cells in the body and prevents them from simulating B cells to secrete antibodies. It also prevents helper T cells from activating CD8 cells that are cytotoxic T cells which are antiviral cells. (van Baarle et al) HIV carries single-stranded RNA that, when coupled with reverse transcriptase, creates HIV DNA. When HIV enters the body, it attaches and fuses with the host cell.…

    • 1063 Words
    • 4 Pages
    Great Essays
  • Improved Essays

    AIDS is the final stage of HIV and going without treatment will lead to death. This is why knowing your status is so important. HIV is treatable and manageable, but you can’t treat what you don’t know. Now that we have a knowledgeable foundation let’s delve into an abbreviated history of HIV/AIDS. AIDS was first discovered in 1981.…

    • 1048 Words
    • 4 Pages
    Improved Essays

Related Topics