A study conducted in 1996 at the Outpatient Clinic for Seasonal Affective Disorder, Department of Biological Psychiatry concluded depression is a trademark of Seasonal Affective Disorder (Willeit, 2008, pg 1503). The study was conducted using a self-referral and referral though the providing psychiatric treatment centers while using previous treatments and diagnoses to establish participant ability. The study showed that because of the weather changes, to include both cold weather and lack of natural light, caused patients who experienced less symptoms of depression during summer months, to have less synaptic serotonin …show more content…
Studies have concluded that individuals who suffer from Seasonal Affective Disorder have an activation of the immune-inflammatory system brought forward by the pathophysiology of depressive disorder they already had (Leu, 2001, index). One patient study concluded that bight light therapy, did not have an effect on the immune-inflammatory system in winter depression, but did conclude there is a direct affect to a person from winter months on the immune systems itself (Leu, 2001, p