Protein: Function And Structure Relationships In DNA Polymerases

Superior Essays
Proteins are large, complex molecules found throughout the body. They are polymers made out of different types of small unites called amino acids. Each amino acid consists of a central carbon atom, which is attached to a hydrogen atom, an amino group, a carboxyl group, and a unique side chain or R group. There are twenty different types of amino acids and each one of them has different chemical properties. Amino acids are held together by covalent peptide bonds therefore the proteins, chains of amino acids, are also called polypeptides. Proteins’ structures have four levels of organization. The primary structure consists of amino acid sequences, which determine the structures and functions of the proteins. Amino acid sequence for each distinct protein is different and for all molecules of the same proteins the sequence is the same. The secondary …show more content…
Essential Cell Biology. 4th ed. New York, NY: Garland Science, 2014. Print. 12 Oct. 2016.
Goodsell, D.s. "DNA Polymerase." RCSB Protein Data Bank RCSB PDB (2000): n. pag. Web. 12 Oct. 2016.
Joyce, Catherine M., and Thomas A. Steitz. "Function and Structure Relationships in DNA Polymerases." Annual Review of Biochemistry 63.1 (1994): 777-822. Web. 23 Oct. 2016.
Lewin, Benjamin. Cells. Sudbury, MA: Jones and Bartlett, 2007. Web. 23 Oct. 2016.
Loeb, Lawrence A., and Raymond J. Monnat. "DNA Polymerases and Human Disease." Nature Reviews Genetics 9.8 (2008): 594-604. Web. 23 Oct. 2016.
Sweasy, Joann B., Julia M. Lauper, and Kristin A. Eckert. "DNA Polymerases and Human Diseases." Radiation Research 166.5 (2006): 693-714. Web. 22 Oct. 2016.
Uemori, Takashi, Yoshizumi Ishino, Hiroyuki Toh, Kiyozo Asada, and Ikunoshin Kato. "Organization and Nucleotide Sequence of the DNA Polymerase Gene from the Archaeon Pyrococcus Furiosus." Nucleic Acids Research 21.2 (1992): 259-65. Web. 23 Oct.

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