DESCRIBE THE ROLE AND FUNCTION OF DIFFERENT CELL TYPES OF INNATE IMMUNITY
Cellular defences are used to differentiate …show more content…
Neutrophils are also granulocytes that are mainly found in the bloodstream and makeup seventy percent of the circulating leukocyte population. They respond quickly to inflammatory signals from infected tissues that are damaged and are bacterial infected. They go through the endothelium of the blood vessels and enter sites of inflammation through the process of chemotaxis. Factors of this process like the IL-8 and C5a take neutrophils from the blood and enter the area of inflammation. This cell recruits several effector mechanisms that fight against infection. It releases antimicrobial peptides and reactive oxygen species through a respiratory burst on to the bacteria and surrounding it to destroy it. As mentioned above it also uses phagocytosis to destroy the pathogen. Lastly, produces a number of pro-inﬂammatory cytokines such as IL-12, IFN-γ and TNF, which are involved in the instigation of subsequent immune responses.
Still on the topic of lymphoid progenitor, there are the Natural killer cells. This natural killer cell which involves the killing of the cancer and virus cells in the blood before the adaptive immune system gets activated. Also called the ‘pit bull’ of the system, it is a part of a little group of large granular lymphocytes. The killer cells are less picky and take out a