Results of animal testing are relied by drug manufacturers in producing their products. If there is a single problem exists in the results, the whole drugs being produced based on the results will be very dangerous to be consumed. Because animal testing do not always give dependable and accurate results, many drugs actually could have opposite impacts on the human consumers. Instead of curing, they could be damaging. The Thalidomide tragedy in 1960 is one of the cases caused by animal testing inaccuracy. Thalidomide is a drug that is designed as a sleeping aid and an antiemetic to help pregnant women overcome morning sickness. However, it was found causing malformations during fetal development although it had passed the safety tests implemented on animals. Approximately 15,000 fetuses were damaged by Thalidomide, about 12,000 of whom were born with birth imperfection, and only 8,000 of them survived their first year of life. Another example of tragedies caused by failure in animal testing is the Vioxx tragedy. Vioxx was created as a COX-2 inhibitor (Wikipedia, 2005). It was believed to have heart-protective effect because that was the result obtained by "dependable" animal testing. Nonetheless, Physicians Committee for Responsible Medicine (PCRM) consultant, John J. Pippin, recently revealed that Vioxx had a heart-damage effect on human (PCRM, 2005). The Vioxx and
Results of animal testing are relied by drug manufacturers in producing their products. If there is a single problem exists in the results, the whole drugs being produced based on the results will be very dangerous to be consumed. Because animal testing do not always give dependable and accurate results, many drugs actually could have opposite impacts on the human consumers. Instead of curing, they could be damaging. The Thalidomide tragedy in 1960 is one of the cases caused by animal testing inaccuracy. Thalidomide is a drug that is designed as a sleeping aid and an antiemetic to help pregnant women overcome morning sickness. However, it was found causing malformations during fetal development although it had passed the safety tests implemented on animals. Approximately 15,000 fetuses were damaged by Thalidomide, about 12,000 of whom were born with birth imperfection, and only 8,000 of them survived their first year of life. Another example of tragedies caused by failure in animal testing is the Vioxx tragedy. Vioxx was created as a COX-2 inhibitor (Wikipedia, 2005). It was believed to have heart-protective effect because that was the result obtained by "dependable" animal testing. Nonetheless, Physicians Committee for Responsible Medicine (PCRM) consultant, John J. Pippin, recently revealed that Vioxx had a heart-damage effect on human (PCRM, 2005). The Vioxx and