X-Linked Agammaglobulinemia Research Paper

Grace Lessman
HES 1823
March 22, 2017
X-Linked Agammaglobulinemia X-linked Agammaglobulinemia, or Bruton’s disease, directly targets the immune system. The function of the immune system is to protect the body from harmful cells that may cause disease. The immune system determines whether a cell is healthy or unhealthy. An unhealthy cell is infected, and once the infection is detected the immune system sends cells called antibodies to respond and terminate the unhealthy cells (Primary Immune Deficiency Diseases). If the antibodies do not respond, then a bodily infection will occur. The antibodies are located sporadically throughout the body. All of the antibodies begin in the bone marrow, and they mature and move to the skin, bloodstream, thymus, lymphatic system, spleen, and mucosal tissue (Primary Immune Deficiency Diseases). The spread out location of the immune cells potentially enable all infections to be quickly responded to. …show more content…
The Gamma globulin is in the blood plasma, and the antibodies within are the main defense cells used by the immune system to fight infection (X-Linked Agammaglobulinemia). When there is a lack of these defensive antibodies, the body is prone to contract infections because there is no response to the unhealthy, infectious cells. An infection that is not fought by antibodies will grow and spread throughout the body with no opposition. Bruton’s disease disables the immune system from successfully fighting off any unhealthy cell