Wound infection is one of the most common causes of death in modern society, especially in people less than 44 years(Shu Fan et al., 2013). Infection is common problem with wound that lead to delay in wound healing and considered as significant mortality and morbidity for patient(Abdul R. Siddiqui and Jack M. Bernstein, 2010). When patient compromised the microorganism from environment or from surrounding skin surface gains access into underlying tissue and characteristic by colonization and growth(Irena Pastar et al., 2013). Colonization is defined as the presence of bacteria that proliferate without patient immune response(Abdul R. Siddiqui and Jack M. Bernstein, 2010). Delay in wound healing characteristic by excessive amount of exudates
