Vitiligo is an illness that was discovered early in the history. There are a lot of civilizations and religions had some opinion about the deficiency of pigmentation in the human body. "Small blemish" was the first and old name that is related to vitiligo more than 1500 years. In the 1879, Moritz Kaposi was the first one who discovered the lack of pigment granules of the vitiligo. In the last century, the name Vitiligo has been used to explain the illness process of losing the pigment cells. Only 1% of the population affected by this illness, so it is a rare condition. Vitiligo is a skin disorder that missing a pigmentation in the skin. In addition, the pigment of the skin (melanocytes) are destructed, and this process can occur and
