Analysis Of The ZIKA Virus

One of the viruses that extend in massive areas of the world, and compel the scientists to look again for this virus is a ZIKA virus. As a result of the rapid prevalence of a ZIKA virus in Asia, Africa and America, it classifies now as an emerging virus, on the other hand, the lack of biological research leads to Increasing the cases of ZIKV in the world. This project sheds light on the mystery novel that allows ZIKV invasion and infection the host cells. A penetration process of ZIKA virus occurs by binding with Gas6 protein or (Growth arrest-specific 6) that leads to activate the Axl protein and release a downstream cascade of signaling within the cells, moreover, Axl signaling plays a significant role in protecting the human cell from stranger guests through a marvelous process called fluid-phase uptake. The hypothesis is a ZIKA virus follows the comparable manner to Axl-dependent Ebola virus uptake and we could summarize this manner in three stages: 1) Infection with ZIKA virus leads to flip the host phospholipids PS from inside to the outside of the host cell and helps to generate ZIKA virions that are surrounded by host lipids 2) ZIKV can interact with indirectly Axl through binding to Gas6. 3) ZIKA utilize AXl and PLC to invade into the host cells through …show more content…
It and most members of the FLAVIVIRIDAE family are under one umbrella known as arboviruses due to they are transmitted to host cells by medial vectors like arthropods. Humen are infected by the bite of various species of female AEDES mosquitoes, and the common species spread in the US are Aedes Aegpti, Aedes albopictus. Because of the loss a pollen against this virus and lack the biology researches so it leads up to continue propagation on new geographic