Vascular Abnormalities Are A Serious Medical Condition That Affect Blood Vessel Formation

1329 Words Dec 1st, 2016 6 Pages
Vascular anomalies are a serious medical condition that affect blood vessel formation in as many as 1 in 10 people (Richter and Suen 2015). Vascular anomalies can be divided into two broad categories: vascular tumors and vascular malformations (Richter and Suen 2015). Vascular tumors, also known as hemangiomas, are characterized by rapid growth with most undergoing involution once the patient has reached a certain age (Richter and Suen 2015). On the other hand, vascular malformations are congenital and thought to grow proportionally with the patient except during cases of trauma, infection or hormonal changes (Richter and Suen 2015). Therefore, these patients would have a normal rate of cell turnover and mitosis but display an error in vascular morphogenesis (Richter and Suen 2015). These vascular malformations can then be subdivided into slow-flow or fast-flow (Richter and Suen 2015). Slow flow malformations are composed of capillary malformations (CMs), venous malformations (VMs), and lymphatic malformations (LMs) (Richter and Suen 2015). High flow malformations are composed of arterial malformations (AMs), arteriovenous fistulas (AVFs), and arteriovenous malformations (AVMs) (Richter and Suen 2015). For the purposes of this grant proposal, we will be focusing on slow flow vascular malformations, more specifically venous malformations (VMs). VMs are the most common type of vascular malformation affecting 1 to 2 per 10,000 births equally between males and females…

Related Documents