Unit Project 4 Essay

1237 Words Dec 1st, 2013 5 Pages
A Typical Cold? by Brent J.F. Hill
Part III—Your Explanation of Sam’s Condition
Objectives and Issues
1. What type of disease is Sam suffering from?
Cystic Fibrosis

2. What tissues and organs does this disease affect? Once you identify all the tissues and organs, briefly explain their respective dysfunction.
Exocrine Glands – glands may become blocked, produce excessive secretions
Sweat Glands – extreme decrease in salt reabsorbtion, resulting in high salt content in sweat.
Lungs – Mucus plugging, chronic bacterial infections, pronounced inflammatory response, damaged airways leading to respiratory insufficiency, progressive decline in pulmonary function.
Male reproductive tract – males with CF are sterile due to degeneration
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The build up of thick, sticky mucus has caused narrowing and/or obstruction of some of the airways in Sam's lungs. This has decreased his surface area, increased the diffusion distance and ultimately reduced his lung function.
3. Do these tests correlate with Sam’s chest x-ray results? Make sure you explain your answer.
Sam's chest x-ray results were “Some hyperinflation and bronchial wall thickening is apparent”.
Reduced FEV1 suggests narrowing of airways (Brand, pg 3) or obstructions (Brand, pg 4). The main problem with obstruction of the airways is getting the air out of the lungs (Brand, pg 5).
So, I believe that the tests do correlate to Sam's chest x-ray results because if he has narrowing or obstruction of his airways that causes problems getting air out of the lungs, then air will become trapped in the lungs causing hyperinflation. The tests also indicated that there is apparent thickening of the bronchial walls which means that they are narrowed due to mucus buildup, which would also make it more difficult to get air out of the lungs.

6. Explain how this disease affects the function of the pulmonary system on a cellular level. You might want to diagram a cell to help with the explanation. Make sure you specifically address osmosis (water movement) and ion transport of the cell.
In a person not affected by CF, chloride ions normally moved out of the epithelial cells to the mucus. Because chloride is negatively

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