Understanding Celiac Disease in Adults
Ilka Perkins-Hagen
East Central College
Understanding Celiac Disease in Adults
Celiac Disease (CD), also called Gluten Enteropathy is an immune-mediated systemic condition triggered by dietary gluten occurring in genetically predisposed individuals. The treatment for CD includes avoiding gluten in the diet, which shows considerable health benefits. Celiac disease is also known as Sprue, Gluten-enteropathy, or Celiac sprue.
Celiac disease damages the villi of the small intestine and affects the absorption of nutrients from food. It occurs in about 1 in 133 Americans or 1% of the population, however, 83% of Americans are un-or miss-diagnosed. Men and women of all ages can develop this genetic autoimmune disease. A number of other disorders including, infertility, reduced bone density, neurological disorders, some cancers, and other autoimmune diseases can develop having CD (BeyondCeliac, n.d.).
One factor is genetic disposition, “the Human Leukocyte Antigen (HLA) genes specifically linked to …show more content…
In those cases, patients might benefit from corticosteroids. Other conditions, such as lymphomas of the small intestine, have to be ruled out (Koehler, Wieser, & Konitzer, 2014, p. 1). A gluten-free diet can be very costly, “therapies developed thus far consist of enzymes designed to digest gluten and the use of inhibitors of paracellular permeability to decrease the migration of gluten peptides into the lamina propria. Other potential therapeutic maneuvers include the binding of gluten by polymers, the use of tissue transglutaminase (TTG) inhibitors and DQ2 or DQ8 blockers, or modulation of cytokine production” (Tennyson, Lewis, & Green, 2009, p. 1). Sporadically, the use of a pharmaceutical agent may be used, such as following occasional gluten exposure or on a chronic basis to lessen the effects of potential accidental ingestion of
Ilka Perkins-Hagen
East Central College
Understanding Celiac Disease in Adults
Celiac Disease (CD), also called Gluten Enteropathy is an immune-mediated systemic condition triggered by dietary gluten occurring in genetically predisposed individuals. The treatment for CD includes avoiding gluten in the diet, which shows considerable health benefits. Celiac disease is also known as Sprue, Gluten-enteropathy, or Celiac sprue.
Celiac disease damages the villi of the small intestine and affects the absorption of nutrients from food. It occurs in about 1 in 133 Americans or 1% of the population, however, 83% of Americans are un-or miss-diagnosed. Men and women of all ages can develop this genetic autoimmune disease. A number of other disorders including, infertility, reduced bone density, neurological disorders, some cancers, and other autoimmune diseases can develop having CD (BeyondCeliac, n.d.).
One factor is genetic disposition, “the Human Leukocyte Antigen (HLA) genes specifically linked to …show more content…
In those cases, patients might benefit from corticosteroids. Other conditions, such as lymphomas of the small intestine, have to be ruled out (Koehler, Wieser, & Konitzer, 2014, p. 1). A gluten-free diet can be very costly, “therapies developed thus far consist of enzymes designed to digest gluten and the use of inhibitors of paracellular permeability to decrease the migration of gluten peptides into the lamina propria. Other potential therapeutic maneuvers include the binding of gluten by polymers, the use of tissue transglutaminase (TTG) inhibitors and DQ2 or DQ8 blockers, or modulation of cytokine production” (Tennyson, Lewis, & Green, 2009, p. 1). Sporadically, the use of a pharmaceutical agent may be used, such as following occasional gluten exposure or on a chronic basis to lessen the effects of potential accidental ingestion of