Repair: Repair is one of the primary reasons for fractionation. The smaller dose fractions separated in time allow normal tissue to recover , and normal tissue with intact repair capacity generally has a better ability to repair damage than tumors.
Redistribution: Cells in some phases of the cell cycle are more radiosensitive than in other . Dose delivery over time allows for redistribution so that tumor cells in a resistant phase continue to cycle into a more sensitive phase.
Reoxygenation: Tumor hypoxia is a condition where tumor cells are deprived of oxygen making them more radioresistant than well oxygenated cells. The oxygenation status may change during treatment and dividing the dose may allow more tumor cells to be eradicated.
Repopulation:
Redistribution: Cells in some phases of the cell cycle are more radiosensitive than in other . Dose delivery over time allows for redistribution so that tumor cells in a resistant phase continue to cycle into a more sensitive phase.
Reoxygenation: Tumor hypoxia is a condition where tumor cells are deprived of oxygen making them more radioresistant than well oxygenated cells. The oxygenation status may change during treatment and dividing the dose may allow more tumor cells to be eradicated.
Repopulation: