The historic area of Thompson's Station is thought to have been settled as early as 1778. Many of the area's earliest settlers arrived between the years 1778 and 1812 as a great wave of immigration swept over the region. In 1780, the first recorded settler staked a claim in the area that was to become Thompson's Station. By 1800, more than 24 homesteads were scattered throughout the area.
The development of the railroad had a large impact on the area. In August of 1855, the first trains arrived in Thompson's Station. The arrival of the rail cars ignited the village's growth and transformed the area into a regional shipping center. The name of Thompson's Station was adopted by the town in 1856. The designation of the town's name came on the
The development of the railroad had a large impact on the area. In August of 1855, the first trains arrived in Thompson's Station. The arrival of the rail cars ignited the village's growth and transformed the area into a regional shipping center. The name of Thompson's Station was adopted by the town in 1856. The designation of the town's name came on the