Varroa destructor (Anderson and Trueman, 2000) is an obligatory ectoparasite of the honeybee (Apis mellifera L). It caused severe damage to populations of this species world-wide in recent years (Le Conte et al., 2010). The direct negative effect of the Varroa on honeybee has well documented (Weinberg and Madel, 1985; Daly et al., 1988, Wienands and Madel, 1988; Marcangeli et al., 1992; Bowen-Walker and Gunn, 2001; Contzen et al., 2004; Yang and Cox-Foster, 2005; Belaïd and Doumandji, 2010; Belaïd et al., 2017). However, in the recent years, scientists have diverted their attention towards the indirect effect by virus transmission, the foulbrood diseases and fungal infection (Hrabak, 2003; Benoit et al., 2004; Tentcheva et al., 2004, Hamdi
