The Significency Relationship Of Neuroblastoma And Microrna-34a

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Neuroblastoma and microRNA- 34a is commonly mentioned together in many articles and studies around the world. With the advance in medicine and new discoveries, there has been found a dependence relation of neuroblastoma with these specific type of microRNA since it has been discovered how it could eliminate cancer eternally. MicroRNA-34a has not only revolutionized scientists but the world in general because of its ability to destroy neuroblastoma but also because is a new natural genetic regulator of a tumor suppressor. Its level of dominance allows it to control different processes like apoptosis, metastasis, and differentiation in the cell cycle. MicroRNAs have taken control over diverse organisms, not only humans but also plants …show more content…
Thanks to discoveries and experiments made by Marie Curie (found radium, useful in radiotherapy for cancer) and Johannes Peter Müller (studied how sensory organs and neurons respond to different kinds of stimuli), medicine has advanced in new treatments, vaccines and even found a cure to diseases like yellow fever, polio, measles. With the increase of these new discoveries and the interest of many students to pursue a medical career, also adding our modern science, there is a possibility to cure or even eradicate a disease that until today hasn’t been able to be exterminated yet. As most of us know, cancer is a disease where abnormal cells split irrepressibly and destroy body tissue and an enormous percentage of our society experiences these diseases which mostly drives them to death. Some of the most common cancer types are breast, prostate, melanoma, etc. They are mostly treated with chemotherapy, radiation therapies, transplantation of stem cell or surgery. Depending on the stage of the tumor, a stem cell transplant procedure would be made in order to infuse healthy cells inside the body and substitute the damaged ones. These treatments can destroy cancer cells that have metastasized to other parts of the body far away from the original …show more content…
Neuroblastoma is a type cancer usually found in the adrenal glands that are located on the upper side of the kidneys. They can begin to cultivate in the chest, neck, bones or pelvis. Most of the time, it affects children from the ages of five or younger and even though it is very rare here in the United States, around 15,000 cases yearly, it is still quite alarming since the rates increase every year (Mayo Clinic). There is a need for medical diagnosis followed by different MRIs and other tests to determine the existence of the cancer tumor. When it comes to the symptoms, throughout the years, doctors and parents have observed signs of fatigue, high fever or loss of appetite. There is also a rare symptom caused by neuroblastoma which is called Opsoclonus-Myoclonus Syndrome. This neurological disorder is mostly related to a disturbance in language, vision, sleep and behavior and it occurs because of the existence of the tumor

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