The Pros And Cons Of Pertussis Vaccines

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Pertussis is a highly contagious respiratory disease, and commonly known as whooping cough because of the uncontrollable coughing which follows infection. However, the immunization against pertussis has two vaccines; DPT and DTaP. DPT contains whole cell pertussis which is pertussis bacteria chemically and heat treated while the DTap version has less bioactive pertussis toxin, both these vaccines are also used to prevent diphtheria and tetanus. DTaP has replaced DPT in numerous countries as it has been deemed safer; DTap will also be the vaccine most referred to as the discontinuation of DPT makes it irrelevant to the purpose of determining whether or not countries should pursue the usage of pertussis vaccines.
While vaccines are promising
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The main reason for using these countries is because all employ an innovative surveillance system by enlisting doctors’ help to report vaccine uptake and weekly updates on which diseases they’re newly diagnosing in patients. This paper aims to prove that there is limited and insufficient evidence to condone the discontinuation of the DTaP vaccine, and the population-level benefits associated with the vaccine significantly outweigh the risks by analyzing yearly immunization rates, pertussis frequencies and encephalitis frequencies. The United States released the DTaP vaccine in 2005 and it was comprised of two versions; one for use in 10-18-year old’s and another for 11- 64-year old’s. Yih et al. (2009) did an analysis of vaccine uptake and adverse events reported between 2005 to 2008. In order to collect accurate data regarding the safety of the new vaccine, the formation of a surveillance system was implemented; supervised by the Vaccine Safety Datalink which is partnership between the Centers of Disease Control (CDC) and 8 managed care organizations (Yih et al. 2009). This system only monitored individuals aged 10 – 64 years as this was the only demographic which could receive the vaccine. 3.3 …show more content…
The study had the same premise as Yih et al. (2009), but described 3 cases of encephalitis which occurred within the risk window for the DTaP vaccine. One patient was an 11-year-old girl who endured encephalopathy for 1 day, she exhibited symptoms 2 days after receiving the DTaP and HBV vaccines. Another was a 28- year old woman who exhibited symptoms 5 days afte3 the DTap vaccine and 10 days after an influenza vaccine, she managed to recover. Lastly, a 12- year old boy was diagnosed with encephalitis 16 days after receiving the DTap vaccine (Chang et al. 2013). All cases eventually recovered, and Chang et al. stated that the 3 case many indicate chance-attributed temporal association not causal. In addition, Chang et al. (2013) noted that in 2009 there were 16, 858 cases of pertussis and 12 infant deaths from pertussis; the CDC lists only 3 cases of encephalitis occurring in 2009 (CDC, 2009). As more deaths were attributed to pertussis than encephalitis - including cases which did not occur post-immunization- there is justification for continuing to administer DTaP, as this shows that pertussis poses more risk due to a greater mortality rate than

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