When a wound’s edges are close together a clot forms. Clots contain fibrin which is a protein that connects the edges of the wound and stops the bleeding. Once a clot has formed and dried it becomes a scab that seals and protects the wound from germs. Epithelium on the edges of the wound goes through regeneration, a process in which new cells of the same function and structure are formed; as the inflammatory responses proceed, epithelium forms under the scab as well. Eventually the wounds edges meet again and the scab is shed. Under the surface, macrophages remove neutrophils and the remaining clot. Then, capillaries grow from the blood vessels around the wound and vascularize that area. All of this is part of fibrosis, in which the clot is
