The Pathogenesis Of Celiac Disease

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Celiac disease is characterized by the specific change in morphology of the epithelial cells within the duodenum and jejunum regions, such as the flattening of the villi linings (villous atrophy), the increase in intestinal gland proliferation (crypt hyperplasia), and the infiltration of lymphocytes into the mucosal cell layers known as the lamina propria and the epithelium.4 The mechanism of the disease has been well studied, and the pathogenesis of CD is now better understood.

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