The negative effect of e-cigarette is throat hit sensation dependent on hardware used and liquid composition. Therefore, equipment is heavier than traditional cigarette and puffing technique requires some training is also the negative aspects of e-cigarette. Not all users manage to quit smoking or reduce consumption are also one of the negative aspects of e-cigarette. Besides that, environmental concern about safe disposal of cartridges and batteries also the negative aspects. The other negative aspects of e-cigarette is impending medicinal regulation in many countries. The intricacies of their use and maintenance may hinder widespread adoption is also the negative
