Thhalidomide Research Paper Solution

Great Essays
One might wake up one morning experiencing morning sickness. She believes it is a common problem while being pregnant. She goes to get the medication Thalidomide from the medicine cabinet, not thinking anything about it. But what the drug company did not tell you was if you are a pregnant woman and you take the medication Thalidomide, your baby may experience some severe problems.
The drug Thalidomide was produced during the 1950s through the 1960s. It was used for women who was experiencing morning sickness during their pregnancy (Mayo Clinic). Chemie Grunenthal, one of the head production companies of the drug, produced Thalidomide as a nontoxic medication. The company labeled Thalidomide with no poisonous potential at that time. Before shipping this drug the company had not proceeded to run through lab test to check the harmful chemical (The Multinational monitor). With every country wanting this drug they shipped crate fulls to the following: 11 European
…show more content…
They wanted to see if they would produce the same human disorders. They gave a pregnant rat and bunny 2 an half pills of Thalidomide and watched for the results. What they discover was nothing, both rats and bunnies were fine. They found no problems with the fetus, but what they could conclude when Thalidomide could hurt their newborn baby (ebscohost). The studies gave them that the drug effects would happen between days 35 through 50. During this time and day the women would not even know if they were pregnant (FFDN). With all of the conclusions of the lab test, the company now had to warn the world of this dangerous drug. In the 1950s drug companies did not have to submit testing results to the appropriate government agencies. The drug manufacturers were not required to reveal some of the results of the tests, which were conducted on “rodents” (Encyclopedia of Drugs and Addictive Substances, Volume

Related Documents

  • Superior Essays

    Should significant resources be expended in order to phase out the use of animals in preclinical testing? Topic Preclinical animal testing is an outdated research method which is inaccurate, unethical, and extremely costly; sponsor companies should expend the necessary resources to begin adopting non-animal testing models as they become available in order to progressively reduce, and ultimately discontinue their use of animals. The contents of this paper will discuss supporting ethical, scientific, and economic evidence, in addition to evaluating possible opposing arguments, and proposing a relevant plan of action. Background Preclinical animal testing has been a boiler plate topic for nearly a century.…

    • 1363 Words
    • 6 Pages
    Superior Essays
  • Improved Essays

    This scared many doctors and parents, therefore many people are trying to avoid the drug…

    • 246 Words
    • 1 Pages
    Improved Essays
  • Improved Essays

    Fluorouracil FDA pregnancy category X which means that studies in animals or humans beings have demonstrated fetal abnormalities or there is evidence of fetal risk based on human experience or both, and the risk of use of the drug in pregnant women clearly outweighs any possible benefit. It is unknown whether or not fluorouracil crosses the placenta. Leucovorin is a Pregnancy category C which indicates that studies have revealed adverse effects on the fetus and there are no controlled studies in women or studies in women and animals are not available. Leucovorin should be given only if the potential benefit justices the potential risk to the fetus because the drug does cross the placenta. Oxaliplatin is a Pregnancy category D which indicates that there is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk from use in pregnant women may be acceptable despite the risk.…

    • 448 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Thalidomide is a sedative created in the 1950s by a West German pharmaceutical company called Chemie Gruenenthal. Originally it was produced to treat morning sickness, and was used a lot by pregnant women. It was advertised to be safe for both mother and child, because as they tested Thalidomide on rats nothing happened to them, no matter how big the dose of Thalidomide was they got. It was the new wonder drug and sold for 4 years in 46 countries across the world until it got pulled from the market in November 1961 due to its teratogenic effects on the fetus.…

    • 612 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    Since the FDA doesn’t approve the DTC drug commercials before they air on TV, around 43% of consumers believed that the drug had to be tested, and 100% approved by the FDA before it can be aired on TV. But, not all drugs have completed their long-term testing before advertising begins. An example of this is the DTC advertised, Vioxx. It was prescribed 1999 to 2004 for arthritis and pain relief, before it was pulled from the shelves for causing heart attacks, and strokes. Vioxx caused 4,540 deaths from January 1st, 1999 to June 30th 2005.…

    • 542 Words
    • 3 Pages
    Decent Essays
  • Improved Essays

    Fentanyl Research Paper

    • 528 Words
    • 3 Pages

    The fentanyl crisis is a problem we should work hard to defeat. Chinese fentanyl suppliers ship the drug to Mexico where it is smuggled into the United States and Canada. Fentanyl is disguised to look like other drugs. “One of the truly terrifying things is the pills are pressed and dyed to look like oxycodone,” said Rendon. “If you are using oxycodone and take fentanyl not knowing it is fentanyl, that is an overdose waiting to happen.…

    • 528 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Trials started only two years before the release, while most drug trials take 8 times longer than that in order to be proven as safe (CCFA, 2016). This is a “Type I error”, which means that the drug was approved as safe to use and was later found to be harmful (Philipson, 2012). Chemie Grünenthal tried to make a deal with an American company, which was rejected, and so eventually made an arrangement with the William S Merrell company in the United States. Chemie Grünenthal should have taken the rejection from the first company as a warning that the drug should not be marketed as safe for even pregnant women. This drug caused many birth defects that resulted in emotional and physical pain and displacement.…

    • 605 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Are you surprised by anything that is said on the website? Why do you think many people are so quick to believe reported statistics? While on the website and reading the article, few things stood out to me. Like many, I was aware of the animal testing epidemic as well as the arguments made by critics and anti-animal testing groups who are opposed to it.…

    • 666 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    New Drug Synthesis

    • 1048 Words
    • 5 Pages

    When a scientist develops a new drug and believes it is ready for people to try, he or she has to go through a process with the FDA to get the drug approved and ready to make it into a person 's everyday life. Most people do not know the process of how a drug goes from chemicals, or any of the substances placed in a medication, to the pill, IV, nose spray, etc. that a patient has in his or her hand. The FDA has a long process that a drug has to go through before that patient can hold it. After a scientist come ups with the makeup of the drug, he or she has to do laboratory tests to check for side effects.…

    • 1048 Words
    • 5 Pages
    Improved Essays
  • Brilliant Essays

    These substances are harmful when consumed in excess in your daily lives, but when an expecting mother uses these drugs, not only does this affect her health, but it also affects the baby growing inside her.…

    • 711 Words
    • 3 Pages
    Brilliant Essays
  • Superior Essays

    Animal Testing Satire

    • 1112 Words
    • 5 Pages

    Imagine having the choice of life or death left in your hands alone. On one end, there is a rat, who is energetically running to find a hiding spot from the broom sweeping across the floor. On the other end, there is a stay-at-home mom, jumped up on the table, violently stabbing at the rat in attempts to scare it away from her. One of them will die. Most people would choose to save the stay-at-home mother with three children and not have a guilty thought cross their mind.…

    • 1112 Words
    • 5 Pages
    Superior Essays
  • Improved Essays

    For about 30 years this drug was used on roughly 4.8 million women and was untested…

    • 1245 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Every person who produces, imports, manufactures, compounds, deals in, dispenses, distributes, or gives away any of the aforesaid drugs shall pay to the said collector a special tax 3. License to “prescribe”- It is unlawful for any person to sell, barter, exchange, or give away any of the aforesaid drugs except in pursuance of a written order of the person to whom such article is sold, bartered, exchanged, or given, on a form to be issued in blank for that purpose by the Commissioner of Internal Revenue. 4. Record keeping- That such physician, dentist, or veterinary surgeon shall keep a record of all such drugs dispensed or distributed, showing the amount dispensed or distributed, the date, and the name and address of the person to whom such drugs are dispensed or…

    • 990 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    The United States Food and Drug Administration is the government agency responsible for regulating food, dietary supplements, drugs, cosmetics, medical devices, biologics and blood products in the United States. The agency is authorized by the government to inspect, test, approve, and set safety standards for foods, chemicals, medical devices, cosmetics, and household devices (britanica.org). Made up of 2,100 scientist including chemists, pharmacologists, physicians, microbiologists, pharmacists, and lawyers, the FDA oversees the production of safe foods and the manufacturing of safe and effective drugs and is responsible in protecting the rights and safety of patients who are used in clinical trials for medical products. (allgov.com). They…

    • 1024 Words
    • 5 Pages
    Improved Essays
  • Superior Essays

    History Of Animal Testing

    • 1408 Words
    • 6 Pages

    Testing in monkeys at 500 times the dose given to the volunteers totally failed to predict the dangerous side effects"…

    • 1408 Words
    • 6 Pages
    Superior Essays