The Importance Of Gene Editing

“In the beginning was the Word, and the Word was with God, and the Word was God” (John 1:1) and I believe the word was ATGCU. The primary or canonical, nucleobases are cytosine (DNA and RNA), guanine (DNA and RNA), adenine (DNA and RNA), thymine (DNA) and uracil (RNA), abbreviated as C, G, A, T, and U, respectively with their ability to selectively bind formed the basis of life on earth. In 2012 with the discovery of CRISPR/Cas9 science acquired the ability to insert, delete and replace DNA sequences which previously were treated as stone carved. When scientists discovered CRISPR /Cas9 based gene edit media across the world regarded it as the revival of genesis where man was acting god. This complex could alter DNA sequence with absolute precision …show more content…
This technology can confer resistance to viral infection and protection from drought in plants (Doudna and Gersbach, 2015). In medical technology gene editing is known to have potential to correct inherited diseases or augment cell therapies designed to attack cancers or regenerate diseased tissue (Doudna and Gersbach, 2015). Gene editing can be achieved through Zink-Finger Nucleus, TALENs, and CRISPR/Cas9. Zinc finger was predominant genome editing technology for over 10 years, but over time the drawbacks of the system emerged (Maeder and Gersbach,2016) . The results with Zinc finger were often inconsistent and were negatively impacted by small uncontrollable activities that naturally occur in the human body (Patrick et al,2014). In addition certain nucleotide triplets could not be targeted, and interactions within a zinc finger array could reduce specificity (Moon and Kim ,2016). In 2009 TAL effectors and their genome targeting abilities were discovered (Maeder and Gershach,2016)). They were used widely in genome editing and transcript activator – like effector nuclease, or