Vinyl chloride’s toxic effects are released via gas or liquid form. First, the route of exposure and how the human body is affected is explained. I have then explained the correlation between mechanisms of action and mode of action, and receiving professional care to eliminate the effects of vinyl chloride. The effects of vinyl chloride on the human body, and how Bradford Hill’s criteria for causation is explained last.
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The route of exposure, based on Thomas Fuller (2015), will affect how the chemical’s composition will take effect in the body. Three routes of exposure include: inhalation, dermal contact, and ingestion. The chemical’s compounds, depending on its solubility and size, will affect the time it takes effect in the …show more content…
Vinyl chloride is a sweet odorless gas that is in a liquid state when in a cool temperature. Therefore, inhalation of vinyl chloride can be unnoticed until symptoms affecting the central nervous system appears. The central nervous system is most affected by inhalation of vinyl chloride and can lead to death. The effects that vinyl chloride has on the human body from the initial exposure to elimination would depend on the route of exposure. Inhalation is the quickest way for the chemical’s compounds to take effect in the human body, that can cause dizziness, visual disturbance, fatigue, and numbness and tingling of the arms and legs. The person can experience disturbance of the heart and respiratory …show more content…
Bradford Hill’s criteria for causation has six types of evidence to prove the relationship between cause and effect, that includes: strength, consistency, specificity, temporality of events, coherence and plausibility, and dose-response relationship. The strength to prove that vinyl chloride does affect the human body is exposure to air concentration that is greater than 3,000 ppm; the occupational safety and health’s permissible exposure limit (pel) is 1 ppm per eight hours shift. Exposure of 8,000 ppm in 5 minutes can cause dizziness (atsdr.cdc.gov., 2014). Consistency would explain the relationship between occurrence of reaction from different studies among different populations. A group of a certain population (group A) that is exposed to inhaling more than 1 ppm of vinyl chloride in an eight- hour shift, as compared to another group of population (group B) exposed to a lower air concentration in the same amount of time, develops a severe or acute reaction. Specificity explains that if both groups were exposed to the exact strength of air concentration in the same amount of time (eight hours), and only group A develops a reaction, that certain people are more prone to quickly react to vinyl chloride. Temporality of events help explain that when exposure to high air concentrations of vinyl chloride is the only toxic chemical exposed to, that it strengthens proof that the effect was caused by vinyl chloride. Coherence and plausibility applied to the data
[Heading 1]
The route of exposure, based on Thomas Fuller (2015), will affect how the chemical’s composition will take effect in the body. Three routes of exposure include: inhalation, dermal contact, and ingestion. The chemical’s compounds, depending on its solubility and size, will affect the time it takes effect in the …show more content…
Vinyl chloride is a sweet odorless gas that is in a liquid state when in a cool temperature. Therefore, inhalation of vinyl chloride can be unnoticed until symptoms affecting the central nervous system appears. The central nervous system is most affected by inhalation of vinyl chloride and can lead to death. The effects that vinyl chloride has on the human body from the initial exposure to elimination would depend on the route of exposure. Inhalation is the quickest way for the chemical’s compounds to take effect in the human body, that can cause dizziness, visual disturbance, fatigue, and numbness and tingling of the arms and legs. The person can experience disturbance of the heart and respiratory …show more content…
Bradford Hill’s criteria for causation has six types of evidence to prove the relationship between cause and effect, that includes: strength, consistency, specificity, temporality of events, coherence and plausibility, and dose-response relationship. The strength to prove that vinyl chloride does affect the human body is exposure to air concentration that is greater than 3,000 ppm; the occupational safety and health’s permissible exposure limit (pel) is 1 ppm per eight hours shift. Exposure of 8,000 ppm in 5 minutes can cause dizziness (atsdr.cdc.gov., 2014). Consistency would explain the relationship between occurrence of reaction from different studies among different populations. A group of a certain population (group A) that is exposed to inhaling more than 1 ppm of vinyl chloride in an eight- hour shift, as compared to another group of population (group B) exposed to a lower air concentration in the same amount of time, develops a severe or acute reaction. Specificity explains that if both groups were exposed to the exact strength of air concentration in the same amount of time (eight hours), and only group A develops a reaction, that certain people are more prone to quickly react to vinyl chloride. Temporality of events help explain that when exposure to high air concentrations of vinyl chloride is the only toxic chemical exposed to, that it strengthens proof that the effect was caused by vinyl chloride. Coherence and plausibility applied to the data