The Effects Of Sarcopenia On Patients With Parkinson 's Disease

2330 Words Sep 27th, 2016 10 Pages
AIM: Sarcopenia has been defined as an involuntary loss of skeletal muscle mass and strength and/or function. The presence of sarcopenia in patients with Parkinson’s disease (PD) may have prognostic effects and may be mistaken for poor therapeutic control of PD.
We aimed to evaluate sarcopenia in patients with PD.
METHODS: One hundred non-demented PD patients, and 95 healthy subjects were included in the study. Avarage-Muscle mass, weight, bone mass, fat mass, basal metabolism rate (BMR), body mass index (BMI) of PD and control groups were measured using bioimpedance analysis.
RESULTS: There were statistically significant difference in average muscle mass of men and women in PD and control groups, 29,83±2,13kg/m2 and 31,96±1,66kg/m2,(p=0,000), and 25,43±2,16kg/m2 and 26,82±1,69kg/m2(p=0,002), respectively. There were statistically significant difference between weight, fat mass, bone mass, BMR and BMI in men in PD and control groups, 76,47±11,71 and 82,64±11,08 (p=0,005); 18,32±6,13 and 21,55±7,84 (p=0,01); 2,91±0,37 and 3,04±0,27 (p=0,03); 1679±236 and 1775±179 (p=0,01); 27,40±3,58 and 28,88±3,52 (p=0,02), respectively. In women there were statistically significant difference between weight and BMR in PD and control groups, 70,30±13,72 and 77,54±17,22 (p=0,04) and 1374±194 and 1482±244 (p=0,03); respectively. In PD group there was no significant correlation between average muscle mass and duration of the disease (r=0.96,p=0.349).
CONCLUSIONS: Our study indicates that…

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