Lisinopril Overview. Lisinopril is categorized as an angiotensin-converting enzyme (ACE) inhibitor. Lisinopril is most commonly utilized as an antihypertensive or in the treatment of congestive heart failure. This medication also has off-label use in the prophylactic treatment of migraines (Schuh‐Hofer et al., 2007, p. 703). Lisinopril is available as an oral tablet and its bioavailability is approximately 25%. Peak antihypertensive effects of lisinopril are reached at approximately six hours after administration which correlates with peak serum levels (Gomez, Cirillo, & Moncloa, 2005, S27). Lisinopril has a half-life of approximately 12 hours.
Mechanism of Action. Lisinopril’s mechanism of action occurs through the inhibition of angiotensin-converting
Mechanism of Action. Lisinopril’s mechanism of action occurs through the inhibition of angiotensin-converting