Double-Placebo-Controlled Study

Hill et al. (2006) conducted a randomized, double-blinded, placebo-controlled study to investigate the difference between β-Alanine supplementation after 4 and 10 weeks and the effect on intense cycling capacity. 25 fit undergraduate and postgraduate fit male participants from the University of Chichester, characterized by low economy and low meat consumption, liberally volunteered to participate. Subjects were not taking any dietary supplements and refrained from supplements 6 weeks before the study. The subjects continued their normal training and diet throughout the study. A cycle performance was completed by each male in order to meet the requirements of the study and then the males were randomized to either the β-Alanine supplemented group (n=13, 8 males continued for 10 weeks) or the placebo group (n=12). The subjects were supplemented each day for 4 or 10 weeks with 8 doses of 100 milligram; the doses increased during the initial four weeks. A percutaneous muscle biopsy of the vastus lateralis was obtained from 6 β-Alanine participants, 8 participants for the 10 weeks, and 6 placebo participants after a cycling test two days before …show more content…
The experimental group was supplemented with equal doses of β-Alanine; however, the subjects continued to train as the participants would have. The participants’ training remained unaltered; if the training was changed, there would have been a possibility that performance would change (2006). The subjects also did not take other supplements during and 6 weeks prior to the study. Therefore, the results were outcomes of the treatments. The study was a placebo-controlled, randomized, and double-blinded, which reduced the variability in results. The extended 10 week β-Alanine supplementation in 8 subjects allowed to examine the extended effect of β-Alanine; during this time, the doses increased. Baseline measurements were recorded prior to, during, and after