The Cloning of Dolly (Sheep) Essay
Natural Sciences – FES 150
Table of Contents INTRODUCTION 3 WHAT IS CLONING? 3 THERAPEUTIC CLONING 3 REPRODUCTIVE CLONING 5 RECOMBINANT CLONING 6 THE BIRTH OF DOLLY (SHEEP) 7 ANNOUNCEMENT TO THE WORLD 8 DOLLY’S FAMILY 9 WAS DOLLY ALREADY “OLD” AT BIRTH? 9 DOLLY’S ARTHRITIS 9 DOLLY’S FINAL ILLNESS 10 WHY WAS DOLLY IMPORTANT? 11 WHAT IS THE LONGTERM SIGNIFICANCE OF DOLLY? 11 DOLLY’S FACT SHEET 12 REFERENCES 13
The possibility of human cloning, raised when Scottish scientists at Roslin Institute created the much-celebrated sheep "Dolly" (Nature 385, 810-13, 1997), aroused worldwide interest and concern because of its scientific implications. A Science …show more content…
The two methods used for reproductive cloning thus far are as follows:
• Cloning using somatic cell nuclear transfer (SCNT). This procedure starts with the removal of the chromosomes from an egg to create an enucleated egg. The chromosomes are replaced with a nucleus taken from a somatic (body) cell of the individual or embryo to be cloned. This cell could be obtained directly from the individual, from cells grown in culture, or from frozen tissue. The egg is then stimulated, and in some cases it starts to divide. If that happens, a series of sequential cell divisions leads to the formation of a blastocyst, or preimplantation embryo. The blastocyst is then transferred to the uterus of an animal. The successful implantation of the blastocyst in a uterus can result in its further development, culminating sometimes in the birth of an animal. This animal will be a clone of the individual that was the donor of the nucleus. Its nuclear DNA has been inherited from only one genetic parent.
The number of times that a given individual can be cloned is limited theoretically only by the number of eggs that can be obtained to accept the somatic cell nuclei and the number of females available to receive developing embryos. If the egg used in this procedure is derived from the same individual that donates the transferred somatic