The Citric Acid Cycle Of The Krebs Cycle

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III )Krebs cycle
The Krebs cycle consists of five major points .
There is in firstly the general overwiew of cellular respiration and in secondly mitochondrie structure then Acetyl-Coa wich contains Production and possible fates then Krebs Cycle wich contains reactions and regulation and finally Glyoxylate cycle.
For the general overwiew of cellular respiration we will talk about cellular respiration.
Cellular respiration is an aerobic phase of catabolism in which organic fuel molecule are oxidi-zed to H2O and CO2.Cellular respiration occurs in three major stages.
The stage one is Acetyl-CoA production with the Glycolysis, The stage two is Acetyl-CoA oxidation with the citric acid cycle and finally the stage three is electron transfer and
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One things importants, the citric acid cycle is an amphibolic pathway.
The krebs cycle a role in anabolism.
For example the Anaplerotic reaction, these reactions replenish the intermediates of the citric cycle that are removed to serve as biosynthetic precursors.
Thry are regulated to keep the level to intermerdiates high enough to support the activity of the citric cycle.
And for finally we will talk about the glyoxylate cycle , the glyoxylate cycle catalyzes the net conversion of acetate to succinate.
Each turn of the glyoxylate cycle consumes two molecule of acetyl-CoA and produces one molecule of
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IV)Oxidative phosphorylation

The respiratory chain corresponds to a combination of protein complexes present in the internal membrane of the mitochondria and responsible, with ATP synthetase, for oxidative phosphorylation.
This process associates the oxidation of NADH and FADH2, both produced in the dif-ferent catabolic pathways of the organism (glycolysis, Krebs cycle), to the production of ATP and this thanks to the formation of proton gradient.

The electron transporters
Throughout the respiratory chain, electrons from NADH and FADH2 will lose energy that will be used to form the proton electrochemical gradient between the intermem-brane space and Mitochondrial matrix. The energy-rich electrons thus recovered will be transported successively via the various complexes:

Complex 1 :NADH dehygrogenase
-Recover electrons from NADH and allowing the transport of 4 protons of the mito-chondrial matrix to the intermembrane space.
-Complex I catalyzes two simultaneous and obligately coupled processes
-It is a proton pump driven by the energy of electron transfer, and the reaction it cata-lyzes is

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