Caffeine:
The athlete benefits from an increase in free fatty acids. This increases endurance capacity by saving glycogen stores, as it enables more fats to be used as fuel thereby reducing and postponing muscle fatigue.
There is also increase in muscle/cell membrane permeability to Ca2+ ions, increasing muscle contractility. and strength are improved. It has been suggested that performance time in a marathon (normal time two and a half hours) may be decreased by as much as 10 minutes with the ingestion of caffeine before and during the