Solventless Reactions: The Aldol Reaction
CH204-01
Fadwa Mekkaoui
Introduction:
An aldol reaction is the formation of a new carbon-carbon bond by the addition of a nucleophile to an electron deficient carbon. The reaction is favorable in Green Chemistry. It demonstrates green principles such as using no solvent and having a high atom economy. In the lab a mixed aldol reaction was performed to synthesize an unsaturated ketone from and aldehyde and ketone. By using an aldehyde, that doesn’t contain any hydrogen’s, one major product is formed. (Figure 1) When grinding 1-Indanone and 3,4-Dimethoxybenzaldehyde a liquid mixture is formed, allowing this reaction to be solventless.
Results/Discussions:
The aldol reaction was very green. The atom
CH204-01
Fadwa Mekkaoui
Introduction:
An aldol reaction is the formation of a new carbon-carbon bond by the addition of a nucleophile to an electron deficient carbon. The reaction is favorable in Green Chemistry. It demonstrates green principles such as using no solvent and having a high atom economy. In the lab a mixed aldol reaction was performed to synthesize an unsaturated ketone from and aldehyde and ketone. By using an aldehyde, that doesn’t contain any hydrogen’s, one major product is formed. (Figure 1) When grinding 1-Indanone and 3,4-Dimethoxybenzaldehyde a liquid mixture is formed, allowing this reaction to be solventless.
Results/Discussions:
The aldol reaction was very green. The atom