Introduction: Definition: o Anti-biotics agents are atoms that kill, or stop the development of, microorganisms, including both microbes and growths. Chemotherapeutic agents are chemicals used in the treatment of infectious diseases or in certain cases, for their prevention. Some of these agents are obtained from MOs or plants, other are synthesized in commercial pharmaceutical laboratories. o Antibiotics contraindicated in pregnancy More than ten million ladies are either pregnant on the other hand lactating whenever. The risks of medication use for these women are unique .What's more to typical physiologic changes that modify the pharmacokinetics of medications; there is the concern of possible teratogenic and toxic effects
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And they are administered antibiotics for many reasons. Because of the special considerations associated with fetal and newborn development, these women constitute a uniquely vulnerable population for which the risks of medication use must be separately assessed. In addition to the pharmacokinetic and pharmacodynamics changes that may occur during pregnancy and lactation that can alter the effectiveness of drugs, there is the added concern of the possible teratogenic and toxic effects that medications may have on the developing fetus and newborn. In general, there is a dearth of pharmacokinetic and pharmacodynamics information regarding the use and proper dosing of Food and Drug Administration (FDA). Body: o Classification of drugs according to their safety for administration by pregnant woman:
The FDA has set up five classes to show the capability of a medication to bring about conception deformities if utilized amid pregnancy. The categories are determined by the reliability of documentation and the risk to benefit ratio. They don't consider any dangers from pharmaceutical specialists or their metabolites in breast milk. The pregnancy classes …show more content…
Example drugs: tramadol, gabapentin, amlodipine, trazodone, prednisone
Class ( D) : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Example drugs: lisinopril, alprazolam, losartan, clonazepam, lorazepam
Class (x) :
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Example drugs: atorvastatin, simvastatin, warfarin, methotrexate, finasteride
Class ( N):
FDA has not classified the drug.
Example drugs: aspirin, oxycodone, hydroxyzine, acetaminophen,
And they are administered antibiotics for many reasons. Because of the special considerations associated with fetal and newborn development, these women constitute a uniquely vulnerable population for which the risks of medication use must be separately assessed. In addition to the pharmacokinetic and pharmacodynamics changes that may occur during pregnancy and lactation that can alter the effectiveness of drugs, there is the added concern of the possible teratogenic and toxic effects that medications may have on the developing fetus and newborn. In general, there is a dearth of pharmacokinetic and pharmacodynamics information regarding the use and proper dosing of Food and Drug Administration (FDA). Body: o Classification of drugs according to their safety for administration by pregnant woman:
The FDA has set up five classes to show the capability of a medication to bring about conception deformities if utilized amid pregnancy. The categories are determined by the reliability of documentation and the risk to benefit ratio. They don't consider any dangers from pharmaceutical specialists or their metabolites in breast milk. The pregnancy classes …show more content…
Example drugs: tramadol, gabapentin, amlodipine, trazodone, prednisone
Class ( D) : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Example drugs: lisinopril, alprazolam, losartan, clonazepam, lorazepam
Class (x) :
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Example drugs: atorvastatin, simvastatin, warfarin, methotrexate, finasteride
Class ( N):
FDA has not classified the drug.
Example drugs: aspirin, oxycodone, hydroxyzine, acetaminophen,