Case Study 1
1. This article featured in Daily mail newspaper. It has been updated on 3rd of June 2010.
2. Tekmira is the pharmaceutical company involved in the research.
3. Ebola was the disease which was being treated. The key symptom of Ebola is haemorrhagic fever and the typical outcome of Ebola is 90% death. It’s transmitted via personal contact e.g. bodily fluid such as blood and saliva.
4. The company used a small interfering RNAs which hold the virus at bay until the immune system is able to take over. Tests in 4 rhesus monkeys showed that 7 daily injections cured 100% of the virus.
5. The main approach was a gene silencing approach that can save monkeys from high doses of the Ebola strain. SiRNAs are implemented which are stretches …show more content…
The virus is thought to be carried by fruit bats. They are the natural hosts of the virus, the disease then gets introduced and spreads to humans through close contact of bodily fluids organs, blood and secretions of the infected animal e.g. chimpanzees, gorillas, monkeys etc. When an individual catches an Ebola virus they develop various symptoms such as fever, headache, fatigue and muscle pain which mostly appear 2 to 21 days after contracting the virus. These symptoms could also potentially present for other infectious diseases such as Malaria and typhoid fever (WHO). Hence it could be difficult to diagnose the disease. However to confirm that the symptoms are caused by Ebola virus the following fundamental investigations are carried …show more content…
However when an individual catches Ebola virus they tend to dehydrate quite quickly therefore its crucial that they have their body fluids, blood pressure, oxygen electrolytes and body organs maintained at the right level. There is an experimental drug known as Zmapp which could be the potential treatment for Ebola disease. However this drug has not yet been tested on humans for safety and effectiveness reason. The product consists of three different combinations of antibody that bind to the protein of the Ebola virus.
Case Study 2
1. The title featured in an article published in guardian on the 29/08/2010
2. The drug is known by two names which are Ivabradine and Procoralan
3. The new condition is heart failure. The key symptoms of this new condition include fatigue, breathlessness, increased heart rate and swollen ankles. Ivabradine is usually used for angina.
4. It was suggested that this drug could prevent up to 10,000 deaths per year, hospital admission could be reduced by a quarter and the NHS could save millions as trails have shown.
5. The trail involved more than 6,500 patients in 37 countries. The patients were already on standard treatments e.g. beta-blockers. They were randomly given additional different doses of the drug and placed into a control group. All the patients involved in this experiment had chronic heart
1. This article featured in Daily mail newspaper. It has been updated on 3rd of June 2010.
2. Tekmira is the pharmaceutical company involved in the research.
3. Ebola was the disease which was being treated. The key symptom of Ebola is haemorrhagic fever and the typical outcome of Ebola is 90% death. It’s transmitted via personal contact e.g. bodily fluid such as blood and saliva.
4. The company used a small interfering RNAs which hold the virus at bay until the immune system is able to take over. Tests in 4 rhesus monkeys showed that 7 daily injections cured 100% of the virus.
5. The main approach was a gene silencing approach that can save monkeys from high doses of the Ebola strain. SiRNAs are implemented which are stretches …show more content…
The virus is thought to be carried by fruit bats. They are the natural hosts of the virus, the disease then gets introduced and spreads to humans through close contact of bodily fluids organs, blood and secretions of the infected animal e.g. chimpanzees, gorillas, monkeys etc. When an individual catches an Ebola virus they develop various symptoms such as fever, headache, fatigue and muscle pain which mostly appear 2 to 21 days after contracting the virus. These symptoms could also potentially present for other infectious diseases such as Malaria and typhoid fever (WHO). Hence it could be difficult to diagnose the disease. However to confirm that the symptoms are caused by Ebola virus the following fundamental investigations are carried …show more content…
However when an individual catches Ebola virus they tend to dehydrate quite quickly therefore its crucial that they have their body fluids, blood pressure, oxygen electrolytes and body organs maintained at the right level. There is an experimental drug known as Zmapp which could be the potential treatment for Ebola disease. However this drug has not yet been tested on humans for safety and effectiveness reason. The product consists of three different combinations of antibody that bind to the protein of the Ebola virus.
Case Study 2
1. The title featured in an article published in guardian on the 29/08/2010
2. The drug is known by two names which are Ivabradine and Procoralan
3. The new condition is heart failure. The key symptoms of this new condition include fatigue, breathlessness, increased heart rate and swollen ankles. Ivabradine is usually used for angina.
4. It was suggested that this drug could prevent up to 10,000 deaths per year, hospital admission could be reduced by a quarter and the NHS could save millions as trails have shown.
5. The trail involved more than 6,500 patients in 37 countries. The patients were already on standard treatments e.g. beta-blockers. They were randomly given additional different doses of the drug and placed into a control group. All the patients involved in this experiment had chronic heart