Takotsubo Cardiomyopathy
Rachell Shempert
APII MW 0800
Takotsubo cardiomyopathy (TC) is also known as stress cardiomyopathy or broken-heart syndrome. The name takotsubo comes from the similarities between the left ventricle and the shape of a Japanese octopus trap. Stress is a common occurance in cases of TC. In approx- imately 70-80% of cases, transient left ventricular systolic dysfunction with apical akinesis and compensatory basal hyperkinesis characterized. The other 20-30% of cases are atypical forms that involve basal or midventricular hypokinesis with apical sparing. A significant hyperadrenergic state appears to be common in cases of TC. Some
Hypothesis to explain TC include: aborted myocardial infarction with spontaneous …show more content…
Excess of catecholamine can cause direct myocardial toxicity or microvascular dysfunction. Emotional stressors have been described to include death, severe illness, or injury of a loved one, the receipt of bad news, a severe argument, an assault, public speaking, financial loss, a car accident, or natural disaster. There have also been physical stressors reported that include surgical procedures such as cholecystectomy, colonoscopy, difficult urinary catheterization, pacemaker implantation, and electrical cardioversion. Physical stressors are observed more in males, while emotional stressors are observed more in women. 90% of people diagnosed with TC are women. TC mimics acute coronary syndrome. Chest pain and difficulty breathing are the most frequent syndrome. Patients rarely present with nausea or vomiting, syncope, or ventricular fibrillation. The most frequent finding on ECGs is ST segment elevation, however
ST elevation can occur in any of the leads. Serum levels of cardiac biomarkers are often elevated in patients with TC. The main feature that distinguishes TC from other
Rachell Shempert
APII MW 0800
Takotsubo cardiomyopathy (TC) is also known as stress cardiomyopathy or broken-heart syndrome. The name takotsubo comes from the similarities between the left ventricle and the shape of a Japanese octopus trap. Stress is a common occurance in cases of TC. In approx- imately 70-80% of cases, transient left ventricular systolic dysfunction with apical akinesis and compensatory basal hyperkinesis characterized. The other 20-30% of cases are atypical forms that involve basal or midventricular hypokinesis with apical sparing. A significant hyperadrenergic state appears to be common in cases of TC. Some
Hypothesis to explain TC include: aborted myocardial infarction with spontaneous …show more content…
Excess of catecholamine can cause direct myocardial toxicity or microvascular dysfunction. Emotional stressors have been described to include death, severe illness, or injury of a loved one, the receipt of bad news, a severe argument, an assault, public speaking, financial loss, a car accident, or natural disaster. There have also been physical stressors reported that include surgical procedures such as cholecystectomy, colonoscopy, difficult urinary catheterization, pacemaker implantation, and electrical cardioversion. Physical stressors are observed more in males, while emotional stressors are observed more in women. 90% of people diagnosed with TC are women. TC mimics acute coronary syndrome. Chest pain and difficulty breathing are the most frequent syndrome. Patients rarely present with nausea or vomiting, syncope, or ventricular fibrillation. The most frequent finding on ECGs is ST segment elevation, however
ST elevation can occur in any of the leads. Serum levels of cardiac biomarkers are often elevated in patients with TC. The main feature that distinguishes TC from other