Systemic Lupus Activity Measure

Improved Essays
With the current available treatments and medication as well as the early diagnosis, SLE is considered a chronic disease with relatively lower mortality rates[90]. SLE symptoms usually present during the first years of obtaining the disease, but can progress quite slowly and be mistaken for other diseases[24][29]. The severity of SLE ranges from benign and can rapid progress to possibly fatal [25]. Fortunately, many patients can manage SLE with medication and live a normal life span [62]. There are several valid systems that measure SLE disease activity and symptom severity, such as the Systemic Lupus Activity Measure (SLAM), SLEDAI, Lupus Activity Index (LAI), European Consensus Lupus Activity Measurement (ECLAM), and British Isles Lupus Activity Group (BILAG) Index [25]. There is no preference of system or most effective measurement for SLE disease activity that is used by physicians [25]. …show more content…
The occurrence of multiple symptom damage is possible as well. Other potential complications could be blood clots, pericarditis, heart attack, stroke, seizures, and kidney failure [30]. Treatment options are available to contain the symptoms, but progression of these symptoms can be life-threatening.
Fatal Systemic Lupus Erythematosus[edit]
In a study on the mortality of SLE patients in 2000 to 2004 by Nossent and colleagues, they determined that 10% of fatalities occurred during the first year and 40% of fatalities occurred after 10 years with the disease [90]. However, one-third of fatalities occurred during remission of the diseases and could potentially be unrelated to SLE [90]. Symptoms of severe infection and cardiovascular events represented 77.78% of death for which a single cause was determined and 41.62% of death for which multiple there were multiple causes.
Rapid Progression Systemic Lupus

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