Generally, there are two types of dynamical synaptic process; Short-Term synaptic Depression (STD), (Loebel., et al 2002), and Short-Term synaptic Facilitation (STF), (Barak., et al, 2007); each class has different phenomenological explanation. For instance, the first one, STD, is suggested to be caused by depletion of the consumed neurotransmitters during the process of synaptic signaling at the axon terminal of a pre-synaptic neuron, whereas the latter, STF, is explained to be induced by an influx of Ca++ into the axonal terminal of the neuron following spike generation, which increases the probability of neurotransmitter release. Interestingly, both forms of STP do not only differ in their neurobiological mechanistic explanation but, also in the manner that they modulate the network activity (Loebel., et al 2002 and Barak., et al, 2007). Regarding the modulation of the firing rate of network activity, an STD was indicated to prefer information transfer for low firing rates, since high-frequency spikes rapidly deactivate the synapse, whereas, STF, however, tends to optimize information transfer for high-frequency bursts, strengthen the
Generally, there are two types of dynamical synaptic process; Short-Term synaptic Depression (STD), (Loebel., et al 2002), and Short-Term synaptic Facilitation (STF), (Barak., et al, 2007); each class has different phenomenological explanation. For instance, the first one, STD, is suggested to be caused by depletion of the consumed neurotransmitters during the process of synaptic signaling at the axon terminal of a pre-synaptic neuron, whereas the latter, STF, is explained to be induced by an influx of Ca++ into the axonal terminal of the neuron following spike generation, which increases the probability of neurotransmitter release. Interestingly, both forms of STP do not only differ in their neurobiological mechanistic explanation but, also in the manner that they modulate the network activity (Loebel., et al 2002 and Barak., et al, 2007). Regarding the modulation of the firing rate of network activity, an STD was indicated to prefer information transfer for low firing rates, since high-frequency spikes rapidly deactivate the synapse, whereas, STF, however, tends to optimize information transfer for high-frequency bursts, strengthen the