Hemophilia is a genetic blood disease in which blood does not clot normally.This disease because certain blood clotting factors are missing or do not work properly.The two main types of hemophilia are A and B.Although the two types have very similar signs and symptoms, they are caused by mutations in different genes.
Hemophilia-A is an X linked bleeding disorder resulting from a defect in a protein known as coagulation factor VIII. Since the disorder is X linked it is expressed mainly in males, who must have mothers who are carriers. Females who express the disorder must have affected fathers and mothers who are carriers, or who are affected. The level of severity of the disorder breeds true in any given family, which indicates that the …show more content…
Blood clots are clumps of different types of blood cells and clotting factors that stop bleeding after an injury to allow wound healing. People with hemophilia, including factor IX deficiency, do not form clots properly. This leads to bleeding that can range from mild to severe. Hemophilia B is the second most common type of hemophilia. Hemophilia B is sometimes called Christmas disease after Stephen Christmas, who was the first patient described with this disease.hemophilia B usually appear during infancy or early …show more content…
Some people may experience pain and swelling in their joints, including the knees, elbows, ankles, shoulders, and hips caused by internal bleeding in the affected joint. When a person with hemophilia is injured, he or she does not bleed harder or faster than a person without hemophilia, but rather he or she bleeds for a longer time. Small cuts or surface bruises are usually not a problem, but more-traumatic injuries may result in serious problems, such as hemorrhage, anemia, and "bleeding episodes."
The main treatment for hemophilia is called replacement therapy. Concentrates of clotting factor VIII (for hemophilia A) or clotting factor IX (for hemophilia B) are slowly dripped or injected into a vein. These infusions help replace the clotting factor that's missing or low.
Clotting factor concentrates can be made from human blood. The blood is treated to prevent the spread of diseases, such as hepatitis. With the current methods of screening and treating donated blood, the risk of getting an infectious disease from human clotting factors is very
Hemophilia-A is an X linked bleeding disorder resulting from a defect in a protein known as coagulation factor VIII. Since the disorder is X linked it is expressed mainly in males, who must have mothers who are carriers. Females who express the disorder must have affected fathers and mothers who are carriers, or who are affected. The level of severity of the disorder breeds true in any given family, which indicates that the …show more content…
Blood clots are clumps of different types of blood cells and clotting factors that stop bleeding after an injury to allow wound healing. People with hemophilia, including factor IX deficiency, do not form clots properly. This leads to bleeding that can range from mild to severe. Hemophilia B is the second most common type of hemophilia. Hemophilia B is sometimes called Christmas disease after Stephen Christmas, who was the first patient described with this disease.hemophilia B usually appear during infancy or early …show more content…
Some people may experience pain and swelling in their joints, including the knees, elbows, ankles, shoulders, and hips caused by internal bleeding in the affected joint. When a person with hemophilia is injured, he or she does not bleed harder or faster than a person without hemophilia, but rather he or she bleeds for a longer time. Small cuts or surface bruises are usually not a problem, but more-traumatic injuries may result in serious problems, such as hemorrhage, anemia, and "bleeding episodes."
The main treatment for hemophilia is called replacement therapy. Concentrates of clotting factor VIII (for hemophilia A) or clotting factor IX (for hemophilia B) are slowly dripped or injected into a vein. These infusions help replace the clotting factor that's missing or low.
Clotting factor concentrates can be made from human blood. The blood is treated to prevent the spread of diseases, such as hepatitis. With the current methods of screening and treating donated blood, the risk of getting an infectious disease from human clotting factors is very