Sickle cell disease is an inherited disorder that is caused by a mutation in the DNA sequences that codes for the beta chain of the hemoglobin protein. Red blood cells are, normally, flexible and round, but with the sickle cell anemia the red blood cells become sticky, rigid, and crescent shaped. The Hemoglobin protein carries oxygen in the red blood cells throughout the body. With the disease, the blood cell’s shape can cause them to get lodged in the blood vessels resulting in the obstruction of blood flow, especially in the smaller arterial vessels in the body This occurrence not only reduces oxygen content to the area of concern, but can be a very painful experience for the victim. People who inherit this disease have two abnormal hemoglobin…
I am in support of the “Sickle Cell Disease Research, Surveillance, Prevention, and Treatment Act of 2015.” Sickle Cell is a serious blood disorder that causes red blood cells to become misshaped. These abnormally shaped red blood cells can get clustered into blood vessels and block blood flow to areas of the body. According to the center of disease and control the number of people with sickle cell in the united states is unknown, but it is prevalent amongst African-Americans occurring in 1 out of 365 births.…
Sickle Cell Anemia is a trait or disorder that is characterized by abnormal hemoglobin which causes red blood cells to become crescentic or sickle shaped, erythrocytes and by speeding up hemolysis, due to substitution of a single amino acid. Low oxygen tension causes polymerization of the abnormal beta chains which changes the shape of the red blood cells to the sickle form. Sickle cells are fragile and they break apart easily they die leaving you with a poor amount of red blood cells. The red blood cells usually live for 120 days before the are replaced. Sickle cells die after an average of less than 20 days.…
The purpose of this study was to determine how family income and sickle cell disease impacted the daily lives of children. This study used a cross-sectional approach to study children with and without sickle cell disease and how they were affected by family income and sickle cell disease in their daily life. During a scheduled clinical visit, those that participated in the study completed the PEDS QL, also known as the Pediatric Quality of Life Inventory, generic core scales parent-proxy or child self-report questionnaire. In this particular study, there was 104 children with sickle cell disease and 74 without sickle cell disease. Compared to children without sickle cell disease, children with sickle cell disease had an increased probability…
: The only cure for sickle cell anaemia is bone marrow transplant also known as stem cell transplant an used for people younger than age 16 because for people older than 16 the risks increases. Finding a donor is difficult, and the procedure has serious risks accompanied with this, which includes death. To prevent complications and relieving symptoms babies and children age 2and younger with sickle cell anaemia should frequent visits to a doctor. Treatments may include medications to reduce pain and prevent complications and blood transfusion etc. Medications used to treat sickle cell anaemia include: • Antibiotics: children with sickle cell anaemia may begin taking antibiotics penicillin about 2 months old and continue taking until they are…
Sickle cell anemia is a genetic disorder of the hemoglobin in our blood. What happens is the red blood cells are abnormally shaped (like a crescent), and they become blocked in the blood vessels, blocking blood flow and oxygen to all the parts of the body. Our blood cells are normally round and flexible which allows for a smooth flow of blood through our bodies, but with sickle cell anemia, this isn’t the case. In this paper we will be looking at a history of sickle cell anemia, who it effects, the symptoms, and how to treat this disorder.…
Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells, causing them to change the normal disc shape to a sickle shape (Bennett). Sickle Cell Disease Association of America estimates that 70,000 to 100,000 individuals have SCD and 3 million individuals have the sickle cell trait (Terrie). Totally not rare at all. Sickle Cell Disease is an disease that affects many people and comes with many dangers, pain, treatments and possible cures.…
Sickle Cell Research: Symptoms, Diagnosis, Treatment and Recent Developments | NIH MedlinePlus the Magazine. Sickle Cell Research: Symptoms, Diagnosis, Treatment and Recent Developments | NIH MedlinePlus the Magazine. https://medlineplus.gov/magazine/issues/winter11/articles/winter11pg18.html. Accessed November 12,…
There are many scriptures throughout the bible that speak about blood. Christ's blood redeems us, brings us into fellowship and peace with God, cleanses us from sin and gives us power over the enemy. The blood of Jesus brings life to us, just as the blood in the physical body carries life. The Lord desires that we walk in divine health (3 Jn 4:6) Consequently for those individuals living with Sickle Cell Disease (SCD), walking in divine health may require receiving routine blood transfusions. It is critical that compatible blood is found and used for these patients.…
Sickle Cell Disease (Anemia) is an autosomal recessive disease caused by a mutation in hemoglobin. Rather than the common disc shape of red blood cells, this disease causes the cells to form in a crescent shape, leaving them fragile and apt to break or clot in small blood vessels, thereby slowing or blocking blood flow. This prevents oxygen from circulating the body properly. As with all autosomal recessive genes, both parents must be carriers in order for their offspring to get the disease.…
Malaria is a vector-borne infectious disease carried by Plasmodium parasites that can be deadly (Lee, 2018). Sickle cell anemia is a form of anemia where an abnormal hemoglobin changes the shape of the red blood cells. Whether or not you have sickle-cell depends on your genotype. Individuals who have the genotype AA (HbA) have "normal" blood and no mutations which can lead them to contracting malaria more easily because they don't have protection. People with the AS genotype, (HbA & HbS) have the sickle cell trait because they have one normal genotype (A) & one non normal (S).…
Genetic Disease: SCD Sickle cell disease is caused by the abnormal change in the haemoglobin gene that slows the flow of blood which causes lack of oxygen to the tissues. Yolanda Smith defines haemoglobin as, “an essential cellular component of the red blood cells that play the role of transporting oxygen in the blood to the bodily tissues where it is required”. ("News-Medical.net", 2015). There are two types of haemoglobin there is HbA that is found in normal red blood cells and HbS one that shows primary the presence of the disease. Sickle cell is characterized by the changes in the shape of the red blood cell from round to a crescent shape when this happens the cells hardens and becomes sticky which makes it difficult to pass through…
According to World Health Organization, Sickle Cell Disease is an inherited blood disorder affecting red blood cells and is the most common genetic diseases in the U.S. Although Sickle Cell Disease largely affects African Americans, it affects other ethnicities too, including those of Mediterranean, Caribbean, South American, Southern European, Indian and those of Middle Eastern descent. The proponents believed that this disease can have a devastating effect on the lives of many people. The bill proponent’s ensured to have access to resources required to better understand the disease and to provide the opportunity of services to those affected by sickle cell disease. And, according to the Centers for Disease Control and Prevention(CDC), it…
Sickle cell disease is a genetic disorder affects the shape of red blood cells. When the shape of red blood cells is changed, it is not able to move through blood vessels nearly as efficiently as red blood cells can in non sickle-cell people. Since these red blood cells can’t move through vessels efficiently, clotting will occur. People with sickle cell disease also have shorter life spans than those who have normal red blood cells. I found sickle cell disease interesting due to it having a high mortality rate, but the disease still being common in the population.…
Hemoglobin job is to allow red blood cells to carry oxygen throughout the body. Abnormal hemoglobin causes the red blood cell to become rigid, sticky, and misshapen. The sickle cell gene can be referred to as Autosomal recessive inheritance, because it is passed down through generations in a pattern of inheritance. A child can be affected by sickle cell is the mother and father passes down a defective gene. If only one parent passes the sickle cell gene the child will have the trait; sickle cell trait produces both normal and sickle cell hemoglobin.…