Sulfa drugs are the common name for a drug category known as sulfonamides which are effective towards a lot of infectious diseases. They are known as one of the first drugs to fix the issues in a time when most drugs could not work to help prevent sickness. Sulfonamides are a group of antimicrobial drugs that contain the sulfanilamide group used to treat certain bacterial infections. The way in which they were discovered is unique.
Sulfa drugs were widely used during World war II, which made a great impact on the mortality rate during the war. The new miracle drug could be carried in powder form and made it easy to take onto the battlefields. Soldiers sprinkled sulfa powders on open wounds and would carry it in a pouch which fit into their belt. After placing the powder into their wounds, the soldier would then wrap gauze around their injured body part. Many lives were saved in WWII versus WWI by the discovery of the sulfa drugs. It was also used by the French foreign legion of Nigeria to treat meningitis. …show more content…
Bacteria survive by multiplying in its host cell, so inhibiting their growth would cause the death of the bacteria. Sulfa drugs work of many various diseases that affect the human body. A sulfa drugs main component is an azo dye. This dye was first made by Paul Gelmo a chemistry student at the University of Vienna in 1908. How sulfa drugs work is by an enzyme inhibitor. This unique inhibitor binds and stops the work of Dihydropteroate Synthase (DHPS). The sulfonamide replaces the 4-Aminobenzoic acid’s. The abbreviation for this is known as (PABA). Different bacteria make their own folic acid which is a type of vitamin B complex present and essential for growth in all living cells. One of the important co-factors for folic acid synthesis in bacteria is 4-Aminobenzoic acid’s
Sulfa drugs were widely used during World war II, which made a great impact on the mortality rate during the war. The new miracle drug could be carried in powder form and made it easy to take onto the battlefields. Soldiers sprinkled sulfa powders on open wounds and would carry it in a pouch which fit into their belt. After placing the powder into their wounds, the soldier would then wrap gauze around their injured body part. Many lives were saved in WWII versus WWI by the discovery of the sulfa drugs. It was also used by the French foreign legion of Nigeria to treat meningitis. …show more content…
Bacteria survive by multiplying in its host cell, so inhibiting their growth would cause the death of the bacteria. Sulfa drugs work of many various diseases that affect the human body. A sulfa drugs main component is an azo dye. This dye was first made by Paul Gelmo a chemistry student at the University of Vienna in 1908. How sulfa drugs work is by an enzyme inhibitor. This unique inhibitor binds and stops the work of Dihydropteroate Synthase (DHPS). The sulfonamide replaces the 4-Aminobenzoic acid’s. The abbreviation for this is known as (PABA). Different bacteria make their own folic acid which is a type of vitamin B complex present and essential for growth in all living cells. One of the important co-factors for folic acid synthesis in bacteria is 4-Aminobenzoic acid’s