Stargardts: Stem Cell-Based Therapy

Improved Essays
A stem cell is simply a cell capable of developing into any other type of cell. It is a biological foundation that hasn’t specialized itself for a specific purpose, however can easily do so for different functions within the body. The cell can be totipotent (able to develop into an organism), pluripotent (able to form tissues of an organism)or multipotent specialized for a certain tissues e.g. blood).
Whilst stem cells are mainly known for coming from embryos, there are a wide variety of other sources from which they come, including the bone marrow, placenta, teeth, amniotic fluid and umbilical cord blood, arguably the largest and best source of these cells. Looking into the future, scientists have predicted great change for medicine due to
…show more content…
Currently there is no direct treatment of the disease, yet ophthalmologists encourage people suffering from the disease to wear dark glasses and a hat when in bright light. Not just does it hinder people from normal activities outside, but it emotionally restricts them. Socializing, driving and other activities often become very emotionally demanding and difficult. Stem cell-based therapy is the only real treatment that is showing promising progress. When treating Stargardts, stem cells generate mature cells from the photoreceptors that die off when a person is affected by the disease. These human stem cells are derived from embryonic and adult tissue. Despite the great progress it has made, there are several concerns including the possibility of a tumour formation, immune rejection and the risk of developing into unwanted cell types. Research so far is taking place in the U.S. and the UK and is called the Advanced Cell Technology (ACT), which involves the transforming of human stem cells into retinal pigment epithelial (RPE). RPE cells break down in Stargardts disease, however are needed to support functions for photoreceptors. By replacing dead cells with healthy ones, there is hope that vision loss can be stopped or slowed …show more content…
The creation of ESC 's is strictly prohibited therefore. Since 2008 however, imported stem cell lines have been allowed to be experimented on to better facilitate stem cell therapy.

UK
The United Kingdom has been a major contributor to bioscience and has been claimed Europe 's leader in stem cell research. Not just to they play a big role in stem cell research nowadays, but Scottish scientist Ian Wilmut successfully cloned the worlds first animal, Dolly the sheep, in 1996. Following this, in 1004, Britain became they third country to allow scientists to clone ESC 's. In 2005, British scientists were the first in the world to successfully clone early-stage embryos. From then on the UK has been leading in stem cell research around the world and conducts many experiments openly.

USA
President w. Bush placed restrictions on the funding of stem cell research due to the various ethical and religious concerns, which led to a rather slow progress in the medical field, after to the halt in research set in place by W. Bush. In 2009, these restrictions were taken away and research continued as before, increasing the process previously

Related Documents

  • Superior Essays

    Is3350 Unit 1 Assignment

    • 3794 Words
    • 16 Pages

    Task 1 – Purpose You must refine the general question/topic down into a specific question for you to research and answer. Task 2 – Sources of information Processing information: Selecting biological ideas relevant to the issue from a range of sources and organising the ideas for reporting. A range needs to involve at least three sources and the sources can be the same type e.g. all from the Internet. Your sources should be recorded and processed in your research document.…

    • 3794 Words
    • 16 Pages
    Superior Essays
  • Great Essays

    Embryonic stem cells, which are different from the iPSCs described here, have faced roadblocks in the form of government defunding their research and the general population raising concerns about the morality of using embryos for research. They also faced challenges when scientists became too optimistic, and hoped the stem cells would prove effectively therapeutic, rather than just a means to perform drug tests. So far these attempts have failed in…

    • 1720 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    Embryonic Stem Cell Research The British Medical Journal, The Lancet, challenged media claims stating that embryonic stem cells are just around the corner. They then quoted Neil Scolding, a neurology researcher at the University of Bristol, saying, “An increasing appreciation of the hazards of embryonic stem cells has rightly prevented the emergence or immediate prospect of any clinical therapies based on such cells. The natural propensity of embryonic stem cells to form tumors and their exhibition of chromosomal abnormalities” (Embryonic). Embryonic stem cells are cells that are obtained from the embryo.…

    • 1049 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Embryonic stem cells (or ES cells) are imperishable, undying. They are the undifferentiated cells which occur in the early embryo of placental mammals, and have the ability to mimic and eventually differentiate into any other cell in the mammalian anatomy. When the mouse ES cell was first identified in 1991, and its human counterpart was isolated seven years later, this immensely powerful cell became the object of many scientific discoveries, political issues, and ethical debates, topics which will be covered in the remainder of this report. ES cells are a critical new frontier in modern medicine, and the spark of its discovery gave rise to the next inferno in modern medicine, and the spark of its discovery gave rise to the next inferno in…

    • 815 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    In 1981, “Martin Evans of Cardiff University, UK, then at the University of Cambridge, is [was] first to identify embryonic stem cells - in mice” (“Stem Cell Timeline: The history of a medical sensation”). The cloning of Dolly, a Finn Dorset sheep, proved that cloning of mammals was possible when using a procedure known as somatic cell nuclear transfer (SCNT). Less than a decade later, a great breakthrough occurred when James Thomson with a group of scientists found the exact mixture and the right technique to withdraw stem cells from an embryo while keeping them viable. “By using the SNCT procedure to produce human embryos genetically matched to patients and using the techniques developed by Thomson to grow human embryonic stem cells, scientists hope one day to be able to replace or regenerate failing human cells and tissues without complication of tissue rejection” (Langwith 17). Thomson’s work laid a foundation for stem cell therapy, where healthy cells will replace diseased or dysfunctional cells.…

    • 1762 Words
    • 8 Pages
    Great Essays
  • Improved Essays

    Stem cells have the ability to grow into a specialized cell once given the chemical signal to do so by the body. Researchers want to one day have the ability to grow failing organs or cure degenerative diseases with the help of stem cells. Somatic stem cells are found in an adult, and can only grow into the special cell from which area it was taken from. This limitation triggers doctors to use a more flexible cell for ongoing and future studies. Theses cells are known as embryonic stem cells, which are harvested from embryos.…

    • 841 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    “The average person doesn't understand what a stem cell is. There's a lack of health literacy in our nation. So the public can't really get into this dialogue because they don't understand the complexity of stem cells, not the faith-based approach, not the ideological or political, but the science behind stem cells.” Richard Carmona Stem cells are an incredible type of cell that is able to develop into many different cell types in the body. When a stem cell divides, it has the possibility of being a stem cell or become a different type of cell that would undergo a certain function such as a muscle cell in the heart.…

    • 984 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    Imagine there was a “miracle” cure for diseases and other ailments; from Parkinson’s disease, to amyotrophic lateral sclerosis- “Lou Gehrig’s Disease”, to spinal cord injury, to cancer, to blindness and diabetes. Though it may sound like a dream come true, it is not something of myth. With a lot of support, funding, and research, stem cells have the potential to eliminate all of the prior and more. Stem cells are an example of the basic building blocks of life: virtually microscopic, unspecialized cells that can evolve to nearly any kind of cell, tissue, or organ. Stem cells can be extracted from a few different places, however, the most efficient and resourceful are ones embryonic in nature.…

    • 2319 Words
    • 10 Pages
    Great Essays
  • Improved Essays

    Although scientific research has come a long way since the beginning of time, it has not done so without some kind of controversy. From Biopsychiatry to the Tuskegee Experiments, it seems as though there cannot be any scientific breakthrough without some kind of ethical issue. Stem cells are another example of a controversial treatment that is taking the medical field by storm. Although it is very controversial, it’s results are truly amazing and beneficial to anyone who is willing to give it a try. Stem cells have the potential to divide into special cells through a process called “mitosis”.…

    • 904 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    The United States of America is the leading country in medical research followed closely by The United Kingdom and Germany. Embryonic stem cell research is a huge opportunity for further advancement. Although some oppose embryonic stem cell research on the grounds of their personal morals, the government has a responsibility to promote research on embryonic stem cells. Embryonic stem cells have the potential to treat incurable diseases; stopping this research would hinder medical treatment and ultimately hurt those affected by diseases that could be treated.…

    • 1487 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    We’ve gone from the hypothesis that stem cells could heal diseases, to gaining evidence that they do. As stated previously the first successful use of ESC occurred in 1998, since then as supported by Ian Murnaghan scientific writer, “Stem cell research has now progressed dramatically and there are countless research studies published each year in scientific journals” (Murnaghan). ESC being the cause of a controversy have quite a bit of attention on them, both good and bad. While some are questioning how morally right it can be to use cells from embryos in the blastocyst stage, others are taking full advantage of the phenomenon that could heal the body just by inserting undecided cells. If research would continue development at that speed, then there’s no telling how far advanced it would be in the next…

    • 1154 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Sachi Pena Mr Van Houten PHI 2600.002 December 5, 2014 Ethicality of Stem Cell Research Is Stem Cell Research Ethical? Stem cells are premature cells that have the ability to turn into different types of cells and are found in five day old embryos. They have the ability to repair damages in certain tissues. When they divide, they either turn into stem cells or change into other cells.…

    • 1579 Words
    • 7 Pages
    Improved Essays
  • Superior Essays

    What makes these cells special is that they have the ability to mature into any cell that is found in the human body. ESC research should be supported for the reason that stem cells can potentially help treat a range of medical problems, stem cells can replace or repair damaged organs, and more importantly the means in which ESC cells are obtained is done ethically. Before introducing the reasons why ESC research should be continued and supported, the history of stem cells needs to be explained. Stem cells were introduced to the medical community in 1998 when a group of scientist led by James Thomas at the University of Wisconsin- Madison developed a technique to isolate and grow ESCs in cell culture.…

    • 1267 Words
    • 6 Pages
    Superior Essays
  • Improved Essays

    The ethical problem that people are confronted with when discussing stem cell research is that in order for this research to happen, a child’s life must cease to exist. The federal government is currently in favor…

    • 911 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    In this case presentation it focuses on research on stem cells to find possible ways to cure many disease. A group of scientists created a line of stem cells out of human embryos that could be used for genetic engineering research in November 1998. When George W. Bush became president he received immense pressure to ban the funding and research for stem cell research, and it led him to ban the proposed funding for the research. To support his actions Bush argued that the stem cells found by the scientists were contaminated with blood products from rodents, and he said that they would provide unreliable research so it would be no longer useful (Van Camp pg. 279).…

    • 1157 Words
    • 5 Pages
    Improved Essays

Related Topics