St. John’s wort (Hypericum perforatum) has been valued for its medicinal attributes for more than 2000 years in Europe and Asia. Traditionally, many civilizations used St. John’s wort to assist wound healing, treat insomnia, depression and anxiety, reduce muscle pain and headache, and relieve upset stomach.
Currently, St. John’s wort remains a popular herbal remedy for mild to moderate depression, menopausal symptoms, skin redness and irritation, minor wounds, mood disorders and sleep disturbances, as well as shows promising results in therapies for cancer, inflammation, and bacterial/viral infections.
In Germany, Saint-John 's-wort is considered as a drug and has been approved/regulated by Commission E (the German equivalent of the USA Food Drug Administration) for the treatment of mild depression, anxiety, and nervous unrest.
Research
Researchers have long-accepted that hypericin is the active antidepressant ingredient of St. John’s wort although some recent research has suggested that hyperforin is actually more active. Either way, without taking into account of side effects, many studies have demonstrated that St. John’s wort is just as effective as conventional drugs to treat mild to moderate depression in both short term and long …show more content…
John’s wort benefits claimed. Two studies, one sponsored by the National Center for Complementary and Alternative Medicine (NCCAM), showed that the herb was no more effective than placebo in treating major depression of moderate severity; ironically, the conventional drugs used in the study did not fare any better than placebo, either (LOL). It should also be noted that these two studies did not directly tested St. John’s wort as a treatment for depression, but as a treatment for mood disorder, which has a broader range of symptoms (that include depression). Nevertheless, the two studies were a big setback for St. John’s