Spironolactone Research Paper

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Spironolactone is related with a well-established exposure of sexual side effects that are dose and duration dependent.16 whereas eplerenone has very low occurrence of sexual side effects. 13,18,21 Sexual side effects of drugs are of specific distress because patients are usually unwilling to bear these effects, and sexual dysfunction is an important reason for unconventionality among hypertensive patients.19,20 Both eplerenone and spironolactone are linked with dose related rise in serum potassium levels.16,18 Patients with primary renal dysfunction or heart failure are at greatest risk of hyperkalemia.22 Both spironolactone and eplerenone are active in decreasing blood pressure (BP) when used as monotherapy15,16 and in combination regimens,

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