Skeletal Muscle

Improved Essays
Skeletal Muscle:

Skeletal muscle makes up approximately 40 percent of a humans total body weight, and contains 50-75 percent of all body proteins, accounting for 30-50 percent of whole body protein turnover (Frontera and Ochala 2015). It contributes significantly to multiple bodily functions both mechanically and metabolically. In terms of our study its main function is to convert chemical energy into mechanical energy allowing individuals to generate force and power, and produce repetitive high speed intermittent movements within sports such as Gaelic Football.
The architecture of skeletal muscle is characterized by a specific and detailed arrangement of muscle fibres, also known as muscle cells or myofibers. Muscle fibres are the mechanically active component of skeletal muscle tissue, making up approximately 80-90 percent of its volume. The remaining volume is made up of intramuscular connective tissue. The intramuscular connective tissue is predominantly made up of collagen, the major structural protein in skeletal muscle (Gillies and Lieber 2011) and ensures an organisation of muscle fibres into fascicles while also contributing importantly to force production (Kjaer 2004).
There are three separated layers of connective tissue found in skeletal muscle. The outer layer that
…show more content…
Myofibrils are threadlike elongated structures found in striated muscle cells that contain these contractile proteins. It is believed that each muscle fibre is made up of thousands of myofibril containing billions of myofilaments (Frontera and Ochala 2015). The building block of these myofibrils is the sarcomeres which are the basic contractile units of skeletal muscle. They are made up of actin and myosin filaments that are divided by a thin sheet of structural proteins called the Z band/ Disk. (Book

Related Documents

  • Decent Essays

    Unit 3 Muscle Lab

    • 248 Words
    • 1 Pages

    There are three types of muscles in the human body: cardiac muscle, smooth muscle and skeletal muscle. For the purpose of our lab we will be focusing only on skeletal muscle. Skeletal muscle is the only voluntary muscle tissue found in the human body. They're attached to bones by tendons and are responsible for all the movements that are consciously controlled such as writing, walking, running, etc. [1].…

    • 248 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    When looking at these under the microscope they are stained the lightest. These muscles are comprised of mainly myofibrils which means they are able to generate lots of force from one contraction. Even though they can generate lots of force they have the fewest mitochondria in them so they fatigue easily. We are doing this experiment to find out what types of muscle fibers the gastrocnemius and forearm muscles are built of. Being built from multiple muscle fiber types is important for maximal fatigue resistant and contraction.…

    • 803 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Repair of membrane is carried out by exocytosis of different intracellular vesicles provoked by rapid calcium. This results in membrane patch being formed to reseal damaged area of the membrane. Findings indicated that dysferlin play a vital role in muscle repairing process. They possibly play a part as a calcium sensor that provokes fusing of vesicle. These findings of functions are not proven however it is based on findings regarding the structure of dysferlin.…

    • 695 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    The goal of this experiment is to understand muscle cell development by studying the proliferation and differentiation progress of C2C12 cells, which are myoblast line isolated from the thigh muscle of adult mice that can be induced to differentiate into skeletal muscle-like cells. C2C12 cells have been subcultured under conditions such as high serum media to maintain their undifferentiated state before they reach 100% confluency. Once the cells reached 100% confluency, they will turn on muscle specific gene such as MyoD that will promote expression of p21 to block cell cycle and will drive differentiation into myotubes. Complete differentiation to myotubes requires shifting the serum to 2% horse serum in the media to slow down the proliferation progress. In this experiment, we will plate the C2C12 cells in three different densities on one 6-well plate and two 8-chamber slides.…

    • 835 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Usually, its bugs that use silk fibers such as insects and spiders they use it to make their cocoons and webs. Elastin and collagen proteins provide a fibrous framework in animal connective tissue. What are proteins? They are large and complex molecules that play many critical roles in the body. Proteins do most of the work in the cells and are required for the structure, function and regulation of the body's tissues and organs.…

    • 1004 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Sarcolema

    • 280 Words
    • 2 Pages

    Within the skeletal muscle cells, there are many organelles. Each cell contains a plasma membrane called the sarcolemma, covering the outer surface of the cell (Ivy Rose). The sarcolemma protects the muscle cell and allows for its shape to be kept. From the sarcolemma, tunnel-like extensions called transverse tubules pass through the muscle fiber (Ivy Rose). These transverse tubules connect the sarcoplasmic reticulum with the sarcolemma (Graham and Parker 117).…

    • 280 Words
    • 2 Pages
    Improved Essays
  • Decent Essays

    Muscle Scaffold

    • 147 Words
    • 1 Pages

    Muscle act as scaffild AT PRESENT ,Muscle scaffold considers one of the promising ways of tissue engineering . It can be done through many ways such as muscle flap , muscle graft , muscle extracellular matrix , muscle acellular scaffold and others Muscle graft refers to the process of moving a healthy muscle or part of it from one part of the body to another one without its blood supply ,on the other hand muscle flap refers to the same but with its blood supply . Compared non vitalized muscle graft with vitalized one ,the non devitalized results in fibrotic tissue and never participate in regeneration .…

    • 147 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    Lab 3: Stimulus strength vs. muscle force production Introduction: The goal of this lab is to determine the relationship between stimulus amplitude (strength) and the contractile properties (i.e. force) of the frog gastrocnemius muscle. Skeletal muscle is composed of bundles of muscle fibers called myofibers. These fibers are themselves composed of myofibrils, which are comprised of the ordered arrangement of actin and myosin. These proteins slide past each other in the presence of calcium ions (Ca2+) and ATP resulting in muscle contraction and relaxation (See Figure).…

    • 677 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Muscles are often only described by large features and classified by a particular region of group of muscles, which does not do the complexity muscle tissue justice. When a skeletal muscle cell is broken down on a microscopic level one is able to truly grasp just how intricate skeletal muscles are along with how they function on a physiological level. Skeletal muscle cells cannot be understood until three key aspects of their structure are enumerated and these are their myofibrils, sarcoplasmic reticulum and t-tubules. To start the myofibrils are the column like structures that run laterally through the inside of the sarcolemma. These rod-like myofibrils are very tightly packed together and are the structures that contract muscles thusly accounting…

    • 296 Words
    • 2 Pages
    Improved Essays
  • Decent Essays

    Myosin: Genomic Analysis

    • 410 Words
    • 2 Pages

    Myosin are a large superfamily of motor molecule which is move along cytoskeletal filaments and interact with actin filaments. That movement requires huge amount of hydrolysis ATP molecules to change the conformation. The genomic analysis thirteen different members of the myosin gene. In addition, the most present myosin type in all eukaryotic cells are: myosin I and myosin II. On the other hand, the less present type of myosin is myosin V. Also, myosin can be divided to two class; conventional myosin which is form the filaments, and unconventional myosin which is can be monomeric.…

    • 410 Words
    • 2 Pages
    Decent Essays
  • Improved Essays

    The maintenance of skeletal muscle mass and metabolic capacity is extremely important for human health and quality of life (Wolfe RR 2006). Skeletal muscle has distinct metabolic and contractile properties that can be influenced by nutrients uptake, microenvironment, and contractile activity. Plasticity and heterogeneity have also been shown to be hallmarks of skeletal muscle as shown by muscle morphology, fiber type, and oxidative capacity. Age, disuse, fasting and various degenerative diseases alter skeletal muscle mass and function. In elderly patients, sarcopenia and failure of basal autophagy (García-Prat L, et al. 2016) is leading to muscle loss, whilst in neurodegenerative diseases the loss of neuromuscular junctions leads to muscle atrophy and even to death (Walston JD.…

    • 1097 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    What Is Muscle Damage?

    • 1321 Words
    • 6 Pages

    This paper will discuss the mechanisms the body uses in order to form regenerated skeletal muscle. Muscle Damage and Injury Before the mechanisms of repair are discussed, it is important to analyze muscle injuries and the effect they have on the muscle tissue. Many muscle injuries are caused more so by mechanical stress, such as in sports or being in a car…

    • 1321 Words
    • 6 Pages
    Improved Essays
  • Great Essays

    Muscular System Essay

    • 1318 Words
    • 6 Pages

    Four tissues/organs of the muscular system are cardiac muscle, skeletal muscle, smooth muscle and the heart. Cardiac muscle is they type of muscle that makes up the heart and is autonomous. The heart is a muscle that is crucial to survival. Smooth muscle lines the inner digestive tract. It contracts to allow food to proceed down the digestive tract.…

    • 1318 Words
    • 6 Pages
    Great Essays
  • Decent Essays

    4 Tissue Types

    • 195 Words
    • 1 Pages

    Skeletal muscle are attached to bones by tendons, and cause movements of body parts in relation to each other by contracting and relaxing. Cardiac muscle tissue is found in the walls of the heart. Smooth muscle tissue forms the walls of our hollow organs. An example is our digestive system and blood vessels. Out of…

    • 195 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    Compare and Contrast different Tissue types – M1 Comparison between Connective Tissue and Epithelial Tissue Similarities: There are many similarities between connective and epithelial tissues. One of which is that both the connective and epithelial tissues have at least 2 layers.…

    • 976 Words
    • 4 Pages
    Improved Essays