Erythrocytes (Red blood cells) are made in bone marrow and lived in the blood stream for 120 days and then die. In hemolytic anemia, the bone marrow is unable to make red blood cells fast enough to meet the body’s need. The severity of the anemia depends on whether the hemolysis is occur in a gradual or abrupt manner and on the extent of erythrocyte destruction. Mild hemolysis can be asymptomatic while the anemia in severe cases can be life threatening. The clinical presentation of HA is depends on the cause of hemolysis. There are many types of HA. The condition can be inherited or acquired. Hemolytic anemia account for about five percent of all anemia. Hemolytic anemia is not specific to any race. Signs and symptoms of HA are diverse and are due to anemia, previous treatment, the extent of compensation, and the underlying disorder. Patients with minimal or long standing HA may be asymptomatic and the disease is often found incidentally during routine laboratory testing. Clinical manifestation of HA includes, iron deficiency in intravascular hemolysis; tachycardia, dyspnea, angina and weakness in severe case of anemia. Persistent hemolysis can result in bilirubin gall stones and the patient may present with pain abdomen. Bronze color skin and diabetes occur in hematosiderosis. Dark color urine is common due to hemoglobinuria. Other signs includes, leg ulcers, jaundice, splenomegaly (Schick, 2016). The patient in the case study presented with many of the signs and symptoms of HA includes, severe chest and abdominal pain, jaundiced eyes, tachycardia, tachypnea. Therefore, Hemolytic anemia can be a second possible
Erythrocytes (Red blood cells) are made in bone marrow and lived in the blood stream for 120 days and then die. In hemolytic anemia, the bone marrow is unable to make red blood cells fast enough to meet the body’s need. The severity of the anemia depends on whether the hemolysis is occur in a gradual or abrupt manner and on the extent of erythrocyte destruction. Mild hemolysis can be asymptomatic while the anemia in severe cases can be life threatening. The clinical presentation of HA is depends on the cause of hemolysis. There are many types of HA. The condition can be inherited or acquired. Hemolytic anemia account for about five percent of all anemia. Hemolytic anemia is not specific to any race. Signs and symptoms of HA are diverse and are due to anemia, previous treatment, the extent of compensation, and the underlying disorder. Patients with minimal or long standing HA may be asymptomatic and the disease is often found incidentally during routine laboratory testing. Clinical manifestation of HA includes, iron deficiency in intravascular hemolysis; tachycardia, dyspnea, angina and weakness in severe case of anemia. Persistent hemolysis can result in bilirubin gall stones and the patient may present with pain abdomen. Bronze color skin and diabetes occur in hematosiderosis. Dark color urine is common due to hemoglobinuria. Other signs includes, leg ulcers, jaundice, splenomegaly (Schick, 2016). The patient in the case study presented with many of the signs and symptoms of HA includes, severe chest and abdominal pain, jaundiced eyes, tachycardia, tachypnea. Therefore, Hemolytic anemia can be a second possible