Sickle Cell Anemia is a trait or disorder that is characterized by abnormal hemoglobin which causes red blood cells to become crescentic or sickle shaped, erythrocytes and by speeding up hemolysis, due to substitution of a single amino acid. Low oxygen tension causes polymerization of the abnormal beta chains which changes the shape of the red blood cells to the sickle form. Sickle cells are fragile and they break apart easily they die leaving you with a poor amount of red blood cells. The red blood cells usually live for 120 days before the are replaced. Sickle cells die after an average of less than 20 days. Without adequate red blood cells circulating in your body oxygen will not be deposited and that will cause fatigue.
Sickle
Sickle