Serotonin : A Neurotransmitter Responsible For Controlling Fundamental Physiological Aspects Of The Body

1264 Words Sep 18th, 2014 6 Pages
Sertraline. Serotonin is a neurotransmitter responsible for controlling fundamental physiological aspects of the body. In the central nervous system (CNS), serotonin has a key role in regulating sleep, appetite, sexual desire and mood, also some cognitive function, including memory, learning and depression. Individuals who suffer from major depressive disorder are associated with decreased availability of serotonin or inefficient levels of serotonin. In addition, suicidal patients have indicated low levels of serotonin which has serve as a linkage between serotonin and depression. So when certain regions of the brain lack serotonin, such as the hypothalamus, amygdala, and cortisol areas which are responsible for cognition and other higher processes, it can have a contributing impact to depression. As such, modulating serotonin at these synapses is the major action of several classes of pharmacological antidepressants.
Researchers and drug companies have aim to provide a drug that enables us to maintain serotonin levels or increase serotonin levels. This drug comes about as Selective serotonin reuptake inhibitors (SSRIs) which blocks the termination of serotonin reuptake by the presynaptic cell, and increasing serotonergic action in depressed patients. Provided by many research and clinical evidence, it has been proven that SSRIs are the most effective and the most commonly prescribed antidepressant medications for the treatment of major depressive disorder (MDD) today.
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