Sepsis: Systemic Infection

Decent Essays
Sepsis is a clinical syndrome of systemic inflammation in response to an infection.1 Sepsis is defined by the presence of systemic inflammatory response syndrome (SIRS) accompanied by a body temperature >38°C, heart rate >90 min 1 or hyperventilation.1 Sepsis is seen in different stages of severity.1 If sepsis is associated with organ dysfunction, it is called severe sepsis.1 If there is also sepsis-induced hypotension, despite resuscitation, it is called septic shock.1 Sepsis develops when the host fails to contain an infection, which results in microthrombi formation, capillary obstruction, microcirculatory alterations, tissue edema and neutrophil recruitment.2 Eventually, this leads to multiple organ failure, which finally results in death.2

Related Documents

  • Improved Essays

    Septic Shock Case Studies

    • 566 Words
    • 3 Pages

    The presence of micro-organisms can confirm sepsis. Septic shock is caused by gram negative bacteria, gram positive bacteria and fungal infections. Due to CC compromised condition he may not be able to resist the infection. To confirm the infection, clotting problems, abnormal liver and kidney function tests, impaired oxegynation, electrolyte imbalances, it is best to do blood tests and cultures. The results of the blood tests, wound cultures and white blood count can specify the type of the microorganism present in the blood.…

    • 566 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    Colorado State Sepsis Initiative Objective To save over 10,000 lives and $200 million in lower healthcare costs over the next five years. Background…

    • 415 Words
    • 2 Pages
    Decent Essays
  • Great Essays

    Having early detection of severe sepsis will decrease mortality rate and length of stay (LOS) within the facility and give the patient the best quality of care. The tools that will increase early detection of severe sepsis is the use of clinical decision support (CDS), a Sepsis cloud and the use of the computerized physician order enter (CPOE) with Clinical decision…

    • 1943 Words
    • 8 Pages
    Great Essays
  • Improved Essays

    Patient had chest x-ray and showed lower lobe pneumonia. This with combination of tachycardia, elevated WBC meets criteria for sepsis. Pathophysiology Lugs are usually the casualty of sepsis the endothelium of the lung is large and lungs…

    • 568 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    Sepsis Case Study Examples

    • 5681 Words
    • 23 Pages

    According to Schouten et al (2008), sepsis involves the activation of the coagulation cascade coupled with down-regulation of anticoagulation and fibrinolysis. An intricate link between inflammation and coagulation exists within the body (Neligan, 2006). When a pathogen is present in the bloodstream or when tissue injury occurs, an inflammatory response occurs. The response causes a stimulation of the immune system to produce interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNFα) (Neligan, 2006). These cytokines are the main catalysts of the inflammatory response and cause the release of several agents including, interleukin-8, histamine, kinins, serotonin, selectins, and neutrophils.…

    • 5681 Words
    • 23 Pages
    Great Essays
  • Improved Essays

    Even though specific treatment does not be present, acute respiratory distress syndrome, treatment of the underlying condition is not therapy, it is essential to use non-invasive ventilation or mechanical ventilation with low tidal volume and conservative fluid management. Since the infection often the cause of ARDS, early administration of suitable antibiotics as wide to cover the suspected agents is essential with a careful evaluation of the patient in order to determine a potential infection source. Sepsis related ARDS is in some cases since it is not solved without control, removal of the blood vessel lines of the infected site, infection drainage of fluid collections, or from surgical debridement or ablation (for instance, ischemic sheet) may be necessary. It may also include deep vein thrombosis, for preventing long-term mechanical ventilation and ICU stay and related complications (DVT) prevent, minimize the prevention, early mobilization, sedation of stress ulcer rotation and skin care, and altitude such as artificial strategy, the head of the bed and using gates suction mechanism to prevent pneumonia caused by respiratory tract. ARDS patients are on bed rest.…

    • 639 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    It can cause inflammation, leaking blood vessels, and decreased blood flow to important organs, including your lungs, liver, and kidneys. If sepsis is not diagnosed and treated quickly, it can lead to septic shock. Shock can result in dangerously low blood pressure and organ failure. What are the causes?…

    • 885 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Transformational change requires a multidisciplinary team approach. Sustained change requires support from both leadership and administration in order to assimilate the dimensions for ongoing improvement and the integration of effective changes into the culture and composition of the unit. Hardwiring change is a theory that necessitates organizers to make it common and effortless to do the right thing. Incorporation of the sepsis bundle process must include all stakeholders in order to gain the cooperation of all parties. The first step in this process is to form a team which brings a diverse personnel together who are given a stake in the outcome and will work to achieve the same goal.…

    • 618 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Hypovolemic Shock

    • 378 Words
    • 2 Pages

    Hypovolemic shock is the result of severe blood/fluid loss causing the heart to inadequately circulate oxygen to the rest of the body (Workman, 2013, pp. 812). In this condition, there is sudden decrease in blood volume within the vascular space causing a drop in mean arterial pressure. This decrease in mean arterial pressure causes a sudden loss in the oxygen carrying capacity of the blood related to the sudden decline in available red blood cells. As the heart is unable to properly pump oxygen to the rest of the body, vital organs begin to shut down, eventually leading to death. It is because of this reason that it must be treated as a medical emergency.…

    • 378 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Sepsis Research Paper

    • 664 Words
    • 3 Pages

    Sepsis is a widespread infection that triggers a whole body inflammatory response. It does not arise on its own but originated from an underlining medical condition such as an infection. Some like to view sepsis as a three stage illness. In this paper I will be discussing what sepsis is, what population is most affected and some of the characteristics or signs and symptoms of the infection.…

    • 664 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    Sepsis Research Paper

    • 1338 Words
    • 6 Pages

    The increase in the mortality rate among the victims of the disease has been related to the lack of knowledge among people about the disease and use of inefficient techniques in identification of the signs, symptoms and intervention SEPSIS AND WHAT I WOULD CHANGE 6 measures. Even after recuperation, sepsis survivors are still likely to suffer from other diseases due to weakened immune systems. The sepsis bundle is a good place to start, but by not trying to drive down lactic acid levels by administering oxygen and allowing the body to use the lactic acid it is producing for fuel during a sepsis crisis patients may have better responses and outcomes to therapy…

    • 1338 Words
    • 6 Pages
    Great Essays
  • Improved Essays

    Tinselsparkleitis

    • 798 Words
    • 4 Pages

    If the infection is not treated properly the patient will die due to lack of white blood cells defending the body’s immune system and blood…

    • 798 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Lower tract acute respiration infections (LT-ARI) has been estimated to cause 75% of all acute illnesses and are said to affect infants and young children worldwide. New respiratory viruses such as: human metapneumovirus (hMPV), new subtypes of human coronaviruses (hCoV), and bocavirus (hBoV), have been linked to LT-ARI. A common factor that affect LT-ARI studied in this experiment is age, although the prevalence is truly unknown. A study was conducted to aim an estimate prevalence of viral co-infection in children hospitalized with LT-ARI and assess whether age impacts the rate of viral co-infections in children. A comparison cohort of 97 UK children were used to compare North and South Europe with Spanish findings.…

    • 1158 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    A few symptoms of inflammation are redness, heat around the infected area, swelling and of course pain within the infected location. Now, inflammation is very important when it come to the immune system as its purpose is to restrict and dispose of anything harmful in the body so the body can start to heal itself. Inflammation is the body’s response to any injuries that you may sustain which prevents spreading and further damaging any surrounding tissue. Inflammations also disposes of cell debris and pathogens as well as starts the repairing process. When cells are injured they release specific inflammatory chemicals to include Histamine (a substance that causes vasodilation and increases vascular permeability) and Kinins (Group of polypeptides…

    • 726 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Essay On Inflammation

    • 490 Words
    • 2 Pages

    6. IN-VIVO STUDY Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process. Inflammatory diseases are very common throughout the world. Rheumatoid arthritis is one of the oldest known diseases of mankind affecting the majority of population no substantial progress has been made in achieving a permanent cure and different types of rheumatic diseases are a major cause of morbidity of the working force.…

    • 490 Words
    • 2 Pages
    Improved Essays