rug interactions are the harmful or beneficial effects of co administered medicinal products, these interaction may be synergistic or antogon istic pharmco kinetics or pharmaco dynamics, drug interactions exists between drugs anddrugs, drug and foods, drugs and herbs, benefits effects include convenience . Reduced toxicity and reduction.
ANTIHISTIMINE, ANTIHISTIMINE, ASTHMA, ANALAGESIC, TYPHOID, HYPERTENSION, TUBERCULOSIS ANTIBIOTICS, FILARIA, RHEUMATOID ARTHRITIS, ANTIPYRITIC, ANTICANCER IMMUNOLOGICAL DISEASES, ECTOPIC PREGNANCY, FEVER, OSTEOARTHRITIS AND ANTIPYRITIC, ANALAGESIC, HIV AIDS, CHICKEN POX,
SALICYLATE, PHENYTOIN, ESTROGENS, HMG COA REDUCTASE INHIBITORS, BARBITURATES, CHLORAMPHENICAL, ANTACIDS, ANTICOAGULANT.
When two or more drugs are administered …show more content…
Nimesulide +tolubutimide, fibirates, salcyclates - displacement of protein binding capacity
Nimesulide +sulphonylureeas-increaese the action of hypoglycemic agent
Brand name of nimesulide - nimulid, nisc, insulide gel
11.HIV AIDS, CHICKEN POX
Aciclair +ketocanazole - synergistic effect
Aciclair +probencid-half life time increases renal clearance
Aciclair +zidovidine - neurotoxic effects
4.OTHER INTRACTION AND ASSOCIATED WITH DISEASES
1.Salicylates
Interference with renal excretion of drugs that undergo active tubular secretion, salicylates renal excretion dependent on urinary pH when large doses used.
Clinically documented INTRACTION
Carbonic anhydrase inhibitors - increased acetazolamide serum concentration, increase salicylate toxicity due to decrease the pH
Coticosteriods-increased the salicylate elimination toxic effect on gastric mucosa
2.Phenytoin
Induces the hepatic microsmal ldrug metabolism
Coticosteriods - decreases the serum corticosteroids levels
Doxycycline - decreases the serum Doxycycline levels
Quinidine - decreases the serum Quinidine levels
Chloramphenical - increased the serum phenytoin
ANTIHISTIMINE, ANTIHISTIMINE, ASTHMA, ANALAGESIC, TYPHOID, HYPERTENSION, TUBERCULOSIS ANTIBIOTICS, FILARIA, RHEUMATOID ARTHRITIS, ANTIPYRITIC, ANTICANCER IMMUNOLOGICAL DISEASES, ECTOPIC PREGNANCY, FEVER, OSTEOARTHRITIS AND ANTIPYRITIC, ANALAGESIC, HIV AIDS, CHICKEN POX,
SALICYLATE, PHENYTOIN, ESTROGENS, HMG COA REDUCTASE INHIBITORS, BARBITURATES, CHLORAMPHENICAL, ANTACIDS, ANTICOAGULANT.
When two or more drugs are administered …show more content…
Nimesulide +tolubutimide, fibirates, salcyclates - displacement of protein binding capacity
Nimesulide +sulphonylureeas-increaese the action of hypoglycemic agent
Brand name of nimesulide - nimulid, nisc, insulide gel
11.HIV AIDS, CHICKEN POX
Aciclair +ketocanazole - synergistic effect
Aciclair +probencid-half life time increases renal clearance
Aciclair +zidovidine - neurotoxic effects
4.OTHER INTRACTION AND ASSOCIATED WITH DISEASES
1.Salicylates
Interference with renal excretion of drugs that undergo active tubular secretion, salicylates renal excretion dependent on urinary pH when large doses used.
Clinically documented INTRACTION
Carbonic anhydrase inhibitors - increased acetazolamide serum concentration, increase salicylate toxicity due to decrease the pH
Coticosteriods-increased the salicylate elimination toxic effect on gastric mucosa
2.Phenytoin
Induces the hepatic microsmal ldrug metabolism
Coticosteriods - decreases the serum corticosteroids levels
Doxycycline - decreases the serum Doxycycline levels
Quinidine - decreases the serum Quinidine levels
Chloramphenical - increased the serum phenytoin