1. INTRODUCTION
The French paradox describes the lowered incidences of coronary heart diseases (CHD) in French people with respect to their diet which consists of high amounts of saturated fats. It is one of the many paradoxes with examples such as the Israeli paradox, which shows that although having a diet low in saturated fats, the Israeli Jews have increased incidences of CHD . This paradoxical event caused elevated interest in the causative factor that can seemingly lower the incidences of CHD in the French. One of the many hypothesises generated was the relatively high consumption of red wine in France when compared to other countries.
Due to multiple researches proving that resveratrol, which is one of the compounds found in red wine, …show more content…
Resveratrol in red wine is just one of the hypothetical explanations of what causes the French paradox, with the others such as catechin and quercetin, explained in chapter 5.3, which are found in red wine that has the same effects as resveratrol. Another possible explanation for the French paradox is the high intake of foods rich in folate or folic acid of the French people, which can reduce the levels of plasma homocysteine which at a high enough level, can cause cardiovascular …show more content…
It produces such an effect through preconditioning, superoxide scavenging, lipid peroxidation, autophagy and inhibition of angiogenesis.
Due to the benefits brought about by resveratrol with regards to CHD, many researches and studies have been focussed on determining the mechanism of action of the effects of resveratrol and its potential usage as a therapeutic or preventive method. This will be further discussed in the next chapter.
3. Uses & effects of resveratrol
In this section, the various usages and the effects of resveratrol will be discussed in the subsequent subsections. Some of the topics that will be explained and discussed are resveratrol and ischaemic preconditioning, its effects on lipid peroxidation, platelet aggregation,
The French paradox describes the lowered incidences of coronary heart diseases (CHD) in French people with respect to their diet which consists of high amounts of saturated fats. It is one of the many paradoxes with examples such as the Israeli paradox, which shows that although having a diet low in saturated fats, the Israeli Jews have increased incidences of CHD . This paradoxical event caused elevated interest in the causative factor that can seemingly lower the incidences of CHD in the French. One of the many hypothesises generated was the relatively high consumption of red wine in France when compared to other countries.
Due to multiple researches proving that resveratrol, which is one of the compounds found in red wine, …show more content…
Resveratrol in red wine is just one of the hypothetical explanations of what causes the French paradox, with the others such as catechin and quercetin, explained in chapter 5.3, which are found in red wine that has the same effects as resveratrol. Another possible explanation for the French paradox is the high intake of foods rich in folate or folic acid of the French people, which can reduce the levels of plasma homocysteine which at a high enough level, can cause cardiovascular …show more content…
It produces such an effect through preconditioning, superoxide scavenging, lipid peroxidation, autophagy and inhibition of angiogenesis.
Due to the benefits brought about by resveratrol with regards to CHD, many researches and studies have been focussed on determining the mechanism of action of the effects of resveratrol and its potential usage as a therapeutic or preventive method. This will be further discussed in the next chapter.
3. Uses & effects of resveratrol
In this section, the various usages and the effects of resveratrol will be discussed in the subsequent subsections. Some of the topics that will be explained and discussed are resveratrol and ischaemic preconditioning, its effects on lipid peroxidation, platelet aggregation,