Research Paper On Zellweger's Syndrome

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Zellweger’s syndrome is rare congenital disorder that is classified as a peroxisome biogenesis disorder. This disease is autosomal recessive and the main cause is directly related to mutations and defects that occur in the genes that are responsible for encoding peroxins. Individuals with this syndrome have mutations in the various 12 PEX genes. These genes are vital for the normal assembly of peroxisomes. This disease can develop when a child is still in the early stages on the newborn period. There are several defects that range from feeding problems, hypotonia, seizures, along with auditory and visual loss. There is an issue with the transmission in the nerve impulses. There is a major issue with the myelin’s function. Usually myelin

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